Panayiotopoulos syndrome: An important childhood autonomic epilepsy to be differentiated from occipital epilepsy and acute non-epileptic disorders

Abstract Panayiotopoulos syndrome is a common multifocal autonomic childhood epileptic disorder with significant clinical, pathophysiological and management implications. It affects otherwise normal children with onset at around 3–6 years. It is characterized by seizures, often prolonged, with predo...

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Bibliographic Details
Published in:Brain & development (Tokyo. 1979) 2010-01, Vol.32 (1), p.4-9
Main Authors: Michael, Michael, Tsatsou, Katerina, Ferrie, Colin D
Format: Article
Language:English
Subjects:
Autonomic seizures
Autonomic status epilepticus
Benign seizures
Brain - physiopathology
Child
Diagnosis, Differential
Epilepsies, Partial - classification
Epilepsies, Partial - diagnosis
Epilepsies, Partial - physiopathology
Epilepsy - classification
Epilepsy - diagnosis
Epilepsy - physiopathology
Humans
Multifocal epilepsy
Neurology
Prognosis
Syndrome
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Description
Summary:Abstract Panayiotopoulos syndrome is a common multifocal autonomic childhood epileptic disorder with significant clinical, pathophysiological and management implications. It affects otherwise normal children with onset at around 3–6 years. It is characterized by seizures, often prolonged, with predominantly autonomic symptoms and mainly ictal vomiting. EEG shows shifting and/or multiple foci, often with occipital dominance. Despite characteristic clinical and EEG manifestations Panayiotopoulos syndrome is often confused with occipital epilepsy and acute non-epileptic disorders such as encephalitis, syncope, cyclic vomiting or atypical migraine. This review aims to describe Panayiotopoulos syndrome on the basis of independent major studies and provide clinical clues for diagnosis and management.
ISSN:0387-7604
1872-7131
DOI:10.1016/j.braindev.2009.03.002