Efficiency and Safety of Long-Term Artrofoon Treatment in Rheumatoid Arthritis

In patients with rheumatoid arthritis, prolongation of artrofoon therapy to 2 years led to maintenance of the positive clinical effect attained after 6-month treatment. Moreover, significant improvement was observed by some parameters (integral pain intensity, swelling index, Ritchie articular index...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2009-09, Vol.148 (3), p.486-488
Main Authors: Petrov, V. I, Babaeva, A. R, Cherevkova, E. V, Kachanova, M. V, Zabolotneva, Yu. A, Tarasov, S. A, Dugina, Yu. L, Sergeeva, S. A
Format: Article
Language:English
Subjects:
Adult
Aged
Antibodies, Monoclonal - adverse effects
Antibodies, Monoclonal - therapeutic use
Antirheumatic Agents - adverse effects
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - drug therapy
artrofoon
Biomedical and Life Sciences
Biomedicine
Cell Biology
Female
Humans
Internal Medicine
Laboratory Medicine
Male
Middle Aged
Pathology
proinflammatory cytokines
rheumatoid arthritis
Treatment Outcome
tumor necrosis factor-a
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Summary:In patients with rheumatoid arthritis, prolongation of artrofoon therapy to 2 years led to maintenance of the positive clinical effect attained after 6-month treatment. Moreover, significant improvement was observed by some parameters (integral pain intensity, swelling index, Ritchie articular index, morning stiffness, and articular score). No side effects related to artrofoon treatment were observed throughout the treatment period in the main group. The results indicate high efficiency and good tolerability of the preparation and attest to advisability of its long-term use.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-010-0743-4