Development of a Hodgkin disease tumor in the neck of a patient who previously had undergone complete excision of a hyaline-vascular Castleman disease neck mass

Castleman disease is an uncommon cause of a neck mass. A benign lymphoproliferative disorder, it may be seen as a self-limited unicentric process or as a fulminant multicentric disease with systemic symptoms. The association between Hodgkin disease and Castleman disease has been debated extensively,...

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Bibliographic Details
Published in:Ear, nose, & throat journal nose, & throat journal, 2010-04, Vol.89 (4), p.E20-E23
Main Authors: Unsal Tuna, Evrim E, Ozbek, Cem, Arda, Nilüfer, Ilkdogan, Evrensel, Dere, Hüseyin, Ozdem, Cafer
Format: Article
Language:English
Subjects:
Adult
Castleman Disease - diagnosis
Castleman Disease - pathology
Castleman Disease - surgery
Follow-Up Studies
Hodgkin Disease - diagnosis
Hodgkin Disease - pathology
Hodgkin Disease - surgery
Humans
Hyalin - ultrastructure
Lymph Node Excision
Lymph Nodes - pathology
Male
Neck - surgery
Otorhinolaryngologic Neoplasms - diagnosis
Otorhinolaryngologic Neoplasms - pathology
Otorhinolaryngologic Neoplasms - surgery
Postoperative Complications - diagnosis
Postoperative Complications - pathology
Postoperative Complications - surgery
Reed-Sternberg Cells - pathology
Reoperation
Tomography, X-Ray Computed
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Summary:Castleman disease is an uncommon cause of a neck mass. A benign lymphoproliferative disorder, it may be seen as a self-limited unicentric process or as a fulminant multicentric disease with systemic symptoms. The association between Hodgkin disease and Castleman disease has been debated extensively, but this association is rare. The associated Hodgkin disease frequently has been of the interfollicular subtype and typically has coexisted with the multicentric plasma-cell variant of Castleman disease. We report a case of mixed-cellularity Hodgkin disease of the neck in a patient previously diagnosed with hyaline-vascular-type Castleman disease who had undergone complete excision of a neck mass 2 years earlier.
ISSN:1942-7522