Magnetic Resonance Imaging of Brain Injury in the High-Risk Term Infant

Magnetic resonance imaging (MRI) is noninvasive and nonionizing and offers excellent soft-tissue contrast and good spatial resolution, providing anatomical detail that cannot be obtained by any other imaging modality. In this review, we discuss the imaging findings in perinatal arterial stroke, hypo...

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Bibliographic Details
Published in:Seminars in perinatology 2010-02, Vol.34 (1), p.67-78
Main Authors: Counsell, Serena J., PhD, Tranter, Sarah L., BSc, Rutherford, Mary A., FRCR
Format: Article
Language:English
Subjects:
brain
Brain Injuries - diagnosis
Brain Injuries - pathology
Cytomegalovirus Infections - diagnosis
Cytomegalovirus Infections - pathology
diffusion-weighted imaging
Herpes Simplex - diagnosis
Herpes Simplex - pathology
Humans
Hypoglycemia - diagnosis
Hypoglycemia - pathology
Hypoxia-Ischemia, Brain - diagnosis
Hypoxia-Ischemia, Brain - pathology
Infant, Newborn
injury
Kernicterus - diagnosis
Kernicterus - pathology
magnetic resonance imaging
Magnetic Resonance Imaging - methods
Magnetic Resonance Imaging - standards
Meningitis - diagnosis
Meningitis - pathology
Neonatal and Perinatal Medicine
neonate
Stroke - diagnosis
Stroke - pathology
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Summary:Magnetic resonance imaging (MRI) is noninvasive and nonionizing and offers excellent soft-tissue contrast and good spatial resolution, providing anatomical detail that cannot be obtained by any other imaging modality. In this review, we discuss the imaging findings in perinatal arterial stroke, hypoxic ischemic encephalopathy, metabolic abnormalities, and infection. Conventional imaging can detect patterns of injury that relate to the etiology and timing of an insult and provide valuable information about prognosis. In many cases, diffusion-weighted imaging provides additional information to conventional MRI, and we recommend its use in all clinical MRI investigations. We also consider the utility of tools such as functional MRI, diffusion tensor imaging, and diffusion tractography in the neonatal population.
ISSN:0146-0005
1558-075X
DOI:10.1053/j.semperi.2009.10.007