Allergy-Preventive Effects of the Flowers of Impatiens textori

The allergy-preventive activity of a 35% EtOH extract (IT) of flowers of Impatiens textori MIQ. was demonstrated in a continuing search for allergy-preventive substances from natural sources. The evaluation of its activity used an in vivo assay method for monitoring the blood flow decrease in the ta...

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Bibliographic Details
Published in:Biological & Pharmaceutical Bulletin 2010/04/01, Vol.33(4), pp.714-716
Main Authors: Iwaoka, Emiko, Oku, Hisae, Iinuma, Munekazu, Ishiguro, Kyoko
Format: Article
Language:English
Subjects:
allergy-preventive effect
Animals
Anti-Allergic Agents - pharmacology
Anti-Allergic Agents - therapeutic use
apigenin
Apigenin - pharmacology
blood flow
Chickens
Egg White
Flavones - pharmacology
Flowers
Glucosides - pharmacology
Hemorheology - drug effects
hen-egg white lysozyme
Hypersensitivity, Delayed - chemically induced
Hypersensitivity, Delayed - physiopathology
Hypersensitivity, Delayed - prevention & control
Impatiens - chemistry
Impatiens textori
luteolin
Luteolin - pharmacology
Mice
Muramidase
Phytotherapy
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Tail - blood supply
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Summary:The allergy-preventive activity of a 35% EtOH extract (IT) of flowers of Impatiens textori MIQ. was demonstrated in a continuing search for allergy-preventive substances from natural sources. The evaluation of its activity used an in vivo assay method for monitoring the blood flow decrease in the tail vein microcirculation of mice subjected to sensitization with hen-egg white lysozyme. Among the principal compounds in IT, apigenin (1), luteolin (3), and luteolin 7-glucoside (4) showed significant allergy-preventive effects.
ISSN:0918-6158
1347-5215
DOI:10.1248/bpb.33.714