Haplotype diversity of 17 Y-chromosomal STR loci in the Bangladeshi population

Abstract Haplotype and allele frequencies of 17 Y-chromosomal STR loci were determined in 216 unrelated Bangladeshi males. AmpFlSTR® Y-filer™ PCR Amplification kit (Applied Biosystems) was used to type the following Y-STR markers: DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b,...

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Published in:Forensic science international : genetics 2010-02, Vol.4 (2), p.e59-e60
Main Authors: Alam, Shafiul, Ali, Md. Eunus, Ferdous, Ahmad, Hossain, Tania, Hasan, Md. Mahamud, Akhteruzzaman, Sharif
Format: Article
Language:English
Subjects:
Analysis of Variance
Asian Continental Ancestry Group - genetics
Bangladesh
Chromosome Mapping
Chromosomes, Human, Pair 17 - genetics
Chromosomes, Human, Y
Gene Amplification
Gene Frequency
Genetic Markers
Genetic Variation
Genetics, Population
Humans
India
Male
Pathology
Polymerase Chain Reaction
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Summary:Abstract Haplotype and allele frequencies of 17 Y-chromosomal STR loci were determined in 216 unrelated Bangladeshi males. AmpFlSTR® Y-filer™ PCR Amplification kit (Applied Biosystems) was used to type the following Y-STR markers: DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS438, DYS439, DYS437, DYS448, DYS458, DYS456, DYS635, and Y-GATA-H4. A total of 211 haplotypes for the 17 Y-STR markers were detected and, of these, 206 haplotypes were unique. The haplotype diversity was 0.9998, indicating a high potential for differentiating between male individuals in this population. Comparison analysis via Analysis of Molecular Variance (AMOVA) and construction of Neighbor Joining Tree revealed a close association of Bangladeshi population with Indian Gaddi and Southern Indian populations.
ISSN:1872-4973
1878-0326
DOI:10.1016/j.fsigen.2009.05.005