Estimation of Standard Liver Volume in Chinese Adult Living Donors

• Published in: Transplantation proceedings 2009-12, Vol.41 (10), p.4052-4056
• Main Authors: Fu-Gui, L, Lu-Nan, Y, Bo, L, Yong, Z, Tian-Fu, W, Ming-Qing, X, Wen-Tao, W, Zhe-Yu, C
• Format: Article
• Language: English
• Subjects: Adult; Body Mass Index; Body Size; Body Surface Area; Body Weight; China; Female; Hepatectomy - methods; Humans; Liver - anatomy & histology; Liver - diagnostic imaging; Living Donors - classification; Male; Middle Aged; Organ Size; Patient Selection; Regression Analysis; Retrospective Studies; Surgery; Tissue and Organ Harvesting - methods; Tomography, X-Ray Computed
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2009.08.079

Abstract Aim To determine a formula predicting the standard liver volume based on body surface area (BSA) or body weight in Chinese adults. Materials and Methods A total of 115 consecutive right-lobe living donors not including the middle hepatic vein underwent right hemi-hepatectomy. No organs were used from prisoners, and no subjects were prisoners. Donor anthropometric data including age, gender, body weight, and body height were recorded prospectively. The weights and volumes of the right lobe liver grafts were measured at the back table. Liver weights and volumes were calculated from the right lobe graft weight and volume obtained at the back table, divided by the proportion of the right lobe on computed tomography. By simple linear regression analysis and stepwise multiple linear regression analysis, we correlated calculated liver volume and body height, body weight, or body surface area. Results The subjects had a mean age of 35.97 ± 9.6 years, and a female-to-male ratio of 60:55. The mean volume of the right lobe was 727.47 ± 136.17 mL, occupying 55.59% ± 6.70% of the whole liver by computed tomography. The volume of the right lobe was 581.73 ± 96.137 mL, and the estimated liver volume was 1053.08 ± 167.56 mL. Females of the same body weight showed a slightly lower liver weight. By simple linear regression analysis and stepwise multiple linear regression analysis, a formula was derived based on body weight. All formulae except the Hong Kong formula overestimated liver volume compared to this formula. Conclusions The formula of standard liver volume, SLV (mL) = 11.508 × body weight (kg) + 334.024, may be applied to estimate liver volumes in Chinese adults.