Allele frequencies of 15 STRs in a representative sample of the Brazilian population

Abstract Allele frequencies for 15 short tandem repeat (STR) loci were obtained from a sample of 12,030 individuals undergoing paternity testing. This sample includes individuals from all States in Brazil, combined according to the current country division into five regions (North, Northeast, Centra...

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Bibliographic Details
Published in:Forensic science international : genetics 2010-02, Vol.4 (2), p.e61-e63
Main Authors: de Assis Poiares, Lilian, de Sá Osorio, Paulo, Spanhol, Fábio Alexandre, Coltre, Sidnei César, Rodenbusch, Rodrigo, Gusmão, Leonor, Largura, Alvaro, Sandrini, Fabiano, da Silva, Cláudia Maria Dornelles
Format: Article
Language:English
Subjects:
Brazil
Gene Frequency
Genetic Carrier Screening
Genetic Variation
Geography
Humans
Male
Microsatellite Repeats - genetics
Paternity
Pathology
Polymerase Chain Reaction - methods
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Summary:Abstract Allele frequencies for 15 short tandem repeat (STR) loci were obtained from a sample of 12,030 individuals undergoing paternity testing. This sample includes individuals from all States in Brazil, combined according to the current country division into five regions (North, Northeast, Central West, Southeast, and South). The most polymorphic loci were D2S1338 and D18S51. All the analysed loci meet Hardy–Weinberg equilibrium expectations. Combined power of discrimination and combined power of exclusion for the 15 tested STR loci were 0.999999999999990 and 0.9999992, respectively. Comparative analysis between populations from different Brazilian macroregions as well as between Brazil and other relevant populations are presented.
ISSN:1872-4973
1878-0326
DOI:10.1016/j.fsigen.2009.05.006