Acute antipsychotic-induced akathisia revisited

Akathisia remains one of the most prevalent and distressful antipsychotic-induced adverse events. Effective and well-tolerated treatment is a major unmet need in akathisia that merits a search for new remedies. Accumulating evidence indicates that agents with marked serotonin-2A receptor antagonism...

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Bibliographic Details
Published in:British journal of psychiatry 2010-02, Vol.196 (2), p.89-91
Main Author: Poyurovsky, Michael
Format: Article
Language:English
Subjects:
Acute Disease
Adenosine
Akathisia
Akathisia, Drug-Induced - drug therapy
Akathisia, Drug-Induced - etiology
Antipsychotic Agents - adverse effects
Antipsychotics
Critical incidents
Dopamine
Drug dosages
Drug therapy
Editorials
Hostility
Humans
Mianserin - analogs & derivatives
Mianserin - pharmacology
Mianserin - therapeutic use
Practice Guidelines as Topic
Psychiatry
Psychosis
Psychotropic drugs
Schizophrenia
Serotonin
Serotonin 5-HT2 Receptor Antagonists
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Summary:Akathisia remains one of the most prevalent and distressful antipsychotic-induced adverse events. Effective and well-tolerated treatment is a major unmet need in akathisia that merits a search for new remedies. Accumulating evidence indicates that agents with marked serotonin-2A receptor antagonism may represent a new class of potential anti-akathisia treatment.
ISSN:0007-1250
1472-1465
DOI:10.1192/bjp.bp.109.070540