Congenital large intestinal hypoganglionosis in a domestic shorthair kitten

An 11-week-old female domestic shorthair kitten presented with a history of constipation since weaning. Abdominal distension was noted on physical examination and abdominal radiographs revealed a large volume of faeces in the descending and transverse colon. Colonoscopy was unremarkable and euthanas...

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Bibliographic Details
Published in:Journal of feline medicine and surgery 2010-05, Vol.12 (5), p.418-420
Main Authors: Roe, Kirsty A.M., Syme, Harriet M., Brooks, Harriet W.
Format: Article
Language:English
Subjects:
Animals
Animals, Newborn
case studies
Cat Diseases - diagnosis
Cats
constipation
Constipation - diagnosis
Constipation - etiology
Constipation - veterinary
digestive system diseases
Euthanasia, Animal
Female
Hirschsprung Disease - complications
Hirschsprung Disease - diagnosis
Hirschsprung Disease - veterinary
Intestine, Large - pathology
kittens
large intestine
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Summary:An 11-week-old female domestic shorthair kitten presented with a history of constipation since weaning. Abdominal distension was noted on physical examination and abdominal radiographs revealed a large volume of faeces in the descending and transverse colon. Colonoscopy was unremarkable and euthanasia was performed at the owners' request. The histological diagnosis of large intestinal hypoganglionosis was made post mortem. This appears to be the first reported case of congenital hypoganglionosis in a kitten with histopathological confirmation of the diagnosis. It may potentially be a more common cause of constipation in kittens and young cats than has previously been suspected.
ISSN:1098-612X
1532-2750
1532-2750
DOI:10.1016/j.jfms.2010.04.001