Relapsing polychondritis: new therapeutic strategies with biological agents

Relapsing polychondritis (RP) is a rare disease of unknown etiology characterized by recurrent episodes of inflammation resulting in the destruction of cartilaginous tissues. We describe a young girl with RP unresponsive to conventional therapy.

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Bibliographic Details
Published in:Rheumatology international 2010-03, Vol.30 (5), p.691-693
Main Authors: Buonuomo, Paola Sabrina, Bracaglia, Claudia, Campana, Andrea, El Hachem, Maya, Diociaiuti, Andrea, Insalaco, Antonella, De Benedetti, Fabrizio, Testa, Beatrice Chiarini, Cortis, Elisabetta, De Vincentiis, Giovanni Carlo, Ugazio, Alberto G.
Format: Article
Language:English
Subjects:
Adolescent
Anti-Inflammatory Agents - therapeutic use
Antibodies, Monoclonal - therapeutic use
Case Report
Fatal Outcome
Female
Humans
Immunosuppressive Agents - therapeutic use
Infliximab
Interleukin 1 Receptor Antagonist Protein - therapeutic use
Intubation, Intratracheal
Medicine
Medicine & Public Health
Polychondritis, Relapsing - complications
Polychondritis, Relapsing - drug therapy
Polychondritis, Relapsing - pathology
Pulse Therapy, Drug
Respiration, Artificial
Respiratory Distress Syndrome, Adult - etiology
Respiratory Distress Syndrome, Adult - therapy
Rheumatology
Steroids - administration & dosage
Tracheostomy
Treatment Outcome
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Description
Summary:Relapsing polychondritis (RP) is a rare disease of unknown etiology characterized by recurrent episodes of inflammation resulting in the destruction of cartilaginous tissues. We describe a young girl with RP unresponsive to conventional therapy.
ISSN:0172-8172
1437-160X
DOI:10.1007/s00296-009-0981-9