Emollient for maintenance therapy after topical corticotherapy in mild psoriasis

• Published in: Experimental dermatology 2009-12, Vol.18 (12), p.1076-1078
• Main Authors: Seité, S., Khemis, A., Rougier, A., Ortonne, J. P.
• Format: Article
• Language: English
• Subjects: Administration, Topical; Adrenal Cortex Hormones - administration & dosage; Adrenal Cortex Hormones - therapeutic use; Biological and medical sciences; clinical trial; corticotherapy; Dermatology; Drug Therapy, Combination; emollient; Emollients - administration & dosage; Emollients - therapeutic use; Humans; Medical sciences; psoriasis; Psoriasis - diagnosis; Psoriasis - drug therapy; Psoriasis - pathology; Psoriasis. Parapsoriasis. Lichen; Quality of Life; Secondary Prevention; Severity of Illness Index; Skin - drug effects; Skin - pathology; Treatment Outcome
• ISSN: 0906-6705; 1600-0625
• DOI: 10.1111/j.1600-0625.2009.00903.x

:  Emollients or moisturizers can act as an important adjunctive therapy of topical treatment in psoriatic patients. However, the interest of emollients has never been clearly demonstrated; i.e. are they able to improve topical treatment efficacy and/or maintain continuous remission of the disease? The aim of this study was to evaluate the effect of an emollient on patients with mild plaque psoriasis during and after standard local corticosteroid therapy. Results showed that the use of an emollient can limit relapses after the end of corticotherapy, and maintain the improvement obtained after 1 month corticotherapy at clinical level (physician global assessment) and skin dryness.