Combining blood flow and tissue Doppler imaging with N-terminal pro-type B natriuretic peptide for risk stratification of clinically stable patients with systolic heart failure

This study was designed to ascertain whether the combination of Doppler assessment of the ratio of mitral blood flow to myocardial early diastolic velocities (E/E(m) ratio) and plasma N-terminal pro-type B natriuretic peptide (NT-proBNP) testing is useful to better stratify patients with stable syst...

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Bibliographic Details
Published in:European journal of echocardiography 2010-05, Vol.11 (4), p.333-340
Main Authors: Dini, Frank Lloyd, Rosa, Gian Marco, Fontanive, Paolo, Santonato, Valeria, Napoli, Anna Maria, Ciuti, Manrico, Di Bello, Vitantonio
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biomarkers - blood
Blood Flow Velocity
Echocardiography, Doppler
Female
Heart Failure, Systolic - blood
Heart Failure, Systolic - diagnostic imaging
Heart Failure, Systolic - mortality
Humans
Male
Middle Aged
Natriuretic Peptide, Brain - blood
Peptide Fragments - blood
Risk Assessment - methods
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Summary:This study was designed to ascertain whether the combination of Doppler assessment of the ratio of mitral blood flow to myocardial early diastolic velocities (E/E(m) ratio) and plasma N-terminal pro-type B natriuretic peptide (NT-proBNP) testing is useful to better stratify patients with stable systolic heart failure (HF). A total of 362 outpatients with chronic systolic HF (left ventricular ejection fraction or=12), 77% in those with the E/E(m) ratio in the intermediate third, and 86% in those with the E/E(m) ratio in the lower third (
ISSN:1525-2167
1532-2114
DOI:10.1093/ejechocard/jep207