Review article: Management of acute severe and near-fatal asthma

Despite a decline in the Australian overall asthma mortality, near‐fatal/critical asthma continues to be a significant management issue for emergency physicians and intensivists. Near‐fatal asthma is a unique subtype of asthma, with a variety of clinical presentations, requiring rapid and aggressive...

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Bibliographic Details
Published in:Emergency medicine Australasia 2009-08, Vol.21 (4), p.259-268
Main Authors: Holley, Anthony D, Boots, Robert J
Format: Article
Language:English
Subjects:
acute severe asthma
Adrenal Cortex Hormones - therapeutic use
Adrenergic alpha-Agonists - therapeutic use
Adrenergic beta-Agonists - therapeutic use
Aged
Albuterol - therapeutic use
Aminophylline - therapeutic use
Asthma - complications
Asthma - diagnosis
Asthma - physiopathology
Asthma - therapy
Bronchodilator Agents - therapeutic use
Calcium Channel Blockers - therapeutic use
Cholinergic Antagonists - therapeutic use
critical asthma
Epinephrine - therapeutic use
Guidelines as Topic
Humans
Ipratropium - therapeutic use
Magnesium Sulfate - therapeutic use
near-fatal asthma
Oxygen - administration & dosage
Oxygen - therapeutic use
Respiration, Artificial - methods
Respiratory Insufficiency - etiology
Respiratory Insufficiency - therapy
Risk Factors
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Summary:Despite a decline in the Australian overall asthma mortality, near‐fatal/critical asthma continues to be a significant management issue for emergency physicians and intensivists. Near‐fatal asthma is a unique subtype of asthma, with a variety of clinical presentations, requiring rapid and aggressive intervention. The pharmacological and non‐pharmacological management of near‐fatal asthma remains very complex. The present review discusses recent advances and evidence for current available strategies targeting this time critical emergency.
ISSN:1742-6731
1742-6723
DOI:10.1111/j.1742-6723.2009.01195.x