Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation

Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation in scuba divers was evaluated. Six volunteers participated in four diving protocols, with 2 wk of recovery between dives. On dive 1, before diving, all divers breathed normall...

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Bibliographic Details
Published in:Journal of applied physiology (1985) 2010-05, Vol.108 (5), p.1077-1083
Main Authors: BOSCO, Gerardo, YANG, Zhong-Jin, DI TANO, Guglielmo, CAMPORESI, Enrico M, FARALLI, Fabio, SAVINI, Fabio, LANDOLFI, Angelo, DORIA, Christian, FANO, Giorgio
Format: Article
Language:English
Subjects:
Administration, Inhalation
Adult
Biological and medical sciences
Blood platelets
Decompression - adverse effects
Decompression Sickness - blood
Decompression Sickness - diagnostic imaging
Decompression Sickness - physiopathology
Decompression Sickness - prevention & control
Diving
Embolism, Air - blood
Embolism, Air - diagnostic imaging
Embolism, Air - physiopathology
Embolism, Air - prevention & control
Fundamental and applied biological sciences. Psychology
Humans
Hyperbaric Oxygenation
Immersion
Inhalation
Integrin beta3 - blood
Male
Middle Aged
Oxygen
Oxygen - administration & dosage
P-Selectin - blood
Platelet Activation
Platelet Membrane Glycoprotein IIb - blood
Respiration
Respiratory system
Scuba & skin diving
Time Factors
Ultrasonography, Doppler
Young Adult
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Summary:Effect of in-water oxygen prebreathing at different depths on decompression-induced bubble formation and platelet activation in scuba divers was evaluated. Six volunteers participated in four diving protocols, with 2 wk of recovery between dives. On dive 1, before diving, all divers breathed normally for 20 min at the surface of the sea (Air). On dive 2, before diving, all divers breathed 100% oxygen for 20 min at the surface of the sea [normobaric oxygenation (NBO)]. On dive 3, before diving, all divers breathed 100% O2 for 20 min at 6 m of seawater [msw; hyperbaric oxygenation (HBO) 1.6 atmospheres absolute (ATA)]. On dive 4, before diving, all divers breathed 100% O2 for 20 min at 12 msw (HBO 2.2 ATA). Then they dove to 30 msw (4 ATA) for 20 min breathing air from scuba. After each dive, blood samples were collected as soon as the divers surfaced. Bubbles were measured at 20 and 50 min after decompression and converted to bubble count estimate (BCE) and numeric bubble grade (NBG). BCE and NBG were significantly lower in NBO than in Air [0.142+/-0.034 vs. 0.191+/-0.066 (P
ISSN:8750-7587
1522-1601
DOI:10.1152/japplphysiol.01058.2009