Immunohistochemistry in the diagnosis of soft tissue tumours

Immunohistochemistry is particularly important in the field of soft tissue tumours because of their variety and the frequent difficulty of diagnosis. The first part of this paper discusses useful or new antibodies, together with others that are no longer of use. The second part is devoted to the rol...

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Bibliographic Details
Published in:Histopathology 2003-07, Vol.43 (1), p.1-16
Main Author: Coindre, J M
Format: Article
Language:English
Subjects:
Antibodies - chemistry
Biomarkers, Tumor - analysis
Humans
immunohistochemistry
Immunohistochemistry - methods
sarcoma
Sarcoma - chemistry
Sarcoma - classification
Sarcoma - pathology
Soft Tissue Neoplasms - chemistry
Soft Tissue Neoplasms - diagnosis
soft tissue tumours
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Summary:Immunohistochemistry is particularly important in the field of soft tissue tumours because of their variety and the frequent difficulty of diagnosis. The first part of this paper discusses useful or new antibodies, together with others that are no longer of use. The second part is devoted to the role of immunohistochemistry in the diagnosis of soft tissue tumours: identification of some rare or atypical benign lesions, identification of non‐mesenchymal malignant tumours, and classification of sarcomas. The respective roles of immunohistochemistry and molecular biology are underlined.
ISSN:0309-0167
1365-2559
DOI:10.1046/j.1365-2559.2003.01639.x