Renal Function and Risk Stratification of Diabetic and Nondiabetic Patients Undergoing Evaluation for Coronary Artery Disease

Objectives The aim of this study was to evaluate the impact of renal function by estimated glomerular filtration rate (eGFR) on risk stratification of diabetic and nondiabetic patients undergoing myocardial perfusion imaging (MPI) by single-photon emission computed tomography for suspected ischemia....

Full description

Saved in:
Bibliographic Details
Published in:JACC. Cardiovascular imaging 2010-07, Vol.3 (7), p.734-745
Main Authors: Hakeem, Abdul, MD, Bhatti, Sabha, MD, Karmali, Kunal N., MD, Dillie, Kathryn S., MD, PhD, Cook, Jeffrey R., MD, Xu, Jiaqiong, PhD, Samad, Zainab, MD, MHS, Chang, Su Min, MD
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cardiovascular
Cardiovascular Diseases - etiology
Cardiovascular Diseases - mortality
Cardiovascular Diseases - physiopathology
Chi-Square Distribution
Chronic Disease
Coronary Artery Disease - complications
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - mortality
Diabetes Complications - etiology
Diabetes Complications - mortality
Diabetes Complications - physiopathology
Female
Glomerular Filtration Rate
Humans
Kaplan-Meier Estimate
Kidney - physiopathology
Kidney Diseases - complications
Kidney Diseases - mortality
Kidney Diseases - physiopathology
Logistic Models
Male
Middle Aged
Myocardial Perfusion Imaging - methods
Odds Ratio
Predictive Value of Tests
Proportional Hazards Models
Retrospective Studies
Risk Assessment
Risk Factors
Severity of Illness Index
Time Factors
Tomography, Emission-Computed, Single-Photon
Veterans
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives The aim of this study was to evaluate the impact of renal function by estimated glomerular filtration rate (eGFR) on risk stratification of diabetic and nondiabetic patients undergoing myocardial perfusion imaging (MPI) by single-photon emission computed tomography for suspected ischemia. Background Coronary artery disease is the leading cause of death among diabetic persons; however, diabetic persons are a very heterogeneous group in terms of cardiovascular risk, necessitating further risk stratification. Methods Patients (n = 1,747, age 65 ± 10 years, 37% diabetic) undergoing MPI were followed for cardiac death (CD) for a mean of 2.15 ± 0.8 years. Chronic kidney disease (CKD) was defined by an eGFR
ISSN:1936-878X
1876-7591
DOI:10.1016/j.jcmg.2010.06.001