Chronic pain following donor nephrectomy – A study of the incidence, nature and impact of chronic post-nephrectomy pain

• Published in: European journal of pain 2010-08, Vol.14 (7), p.732-734
• Main Authors: Owen, Margaret, Lorgelly, Paula, Serpell, Mick
• Format: Article
• Language: English
• Subjects: Activities of Daily Living; Adult; Anesthesia & Perioperative Care; Chronic Disease - epidemiology; Chronic pain; Donor nephrectomy; Health Surveys; Humans; Incidence; Kidney Transplantation - adverse effects; Living Donors; Nephrectomy - adverse effects; Neuropathic pain; Organ donation; Pain Measurement; Pain Medicine; Pain, Postoperative - epidemiology; Pain, Postoperative - etiology; Post-surgical pain; Quality of Life
• ISSN: 1090-3801; 1532-2149
• DOI: 10.1016/j.ejpain.2009.11.013

Abstract Chronic pain is a consequence of some types of surgery, but its incidence following open donor nephrectomy has never been investigated. We surveyed 123 patients who underwent open donor nephrectomy at our institution over a 10-year period, to determine the incidence, severity and nature of chronic pain and its effect on quality of life. Of the 81 (66%) responders, 27 (33%) had experienced prolonged pain, and 21 (26%) still had chronic pain related to their surgery. The overall incidence of severe, disabling pain (visual analogue score ⩾7) was 12% and of neuropathic pain was 14%. The average loss in quality adjusted life years (QALYs) was 1.053 for chronic pain sufferers, but was 1.851 for those who suffered specifically from neuropathic pain. Only one third of patients with chronic pain were receiving any treatment, and none were receiving neuropathic adjuvants or specialist pain management interventions. We conclude that the incidence of chronic pain following donor nephrectomy is underestimated and therefore under managed. Given the voluntary and altruistic nature of this procedure, and the enormous personal and social benefits which result from successful donor transplantation, those involved with the preparation and post-operative management should be more aware of, and actively question donors about chronic pain so that diagnosis and appropriate therapy can be commenced as early as possible.