Regional effects of neurotensin on the electrically stimulated release of [3H]dopamine and [14C]acetylcholine in the rat nucleus accumbens

This study has shown that neurotensin (NT) increases the electrically stimulated release of [3H]DA to a similar extent in all but the extreme caudolateral area of the rat nucleus accumbens and appears to modulate DA release equally in the medial and lateral zones of this brain area. The simultaneous...

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Bibliographic Details
Published in:Neurochemical research 1992-11, Vol.17 (11), p.1143-1146
Main Authors: REYNEKE, L, RUSSELL, V. A, TALJAARD, J. J. F
Format: Article
Language:English
Subjects:
Acetylcholine - metabolism
Animals
Biochemistry and metabolism
Biological and medical sciences
Carbon Radioisotopes
Central nervous system
Dopamine - metabolism
Electric Stimulation
Fundamental and applied biological sciences. Psychology
Male
Neurotensin - pharmacology
Nucleus Accumbens - drug effects
Nucleus Accumbens - metabolism
Perfusion
Rats
Rats, Wistar
Tritium
Vertebrates: nervous system and sense organs
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Summary:This study has shown that neurotensin (NT) increases the electrically stimulated release of [3H]DA to a similar extent in all but the extreme caudolateral area of the rat nucleus accumbens and appears to modulate DA release equally in the medial and lateral zones of this brain area. The simultaneous release of ACh was not significantly affected by NT.
ISSN:0364-3190
1573-6903
DOI:10.1007/BF00967292