Percutaneous image-guided radiofrequency ablation of liver tumors

The development of image-guided percutaneous techniques for local tumor ablation has been one of the major advances in the treatment of liver malignancies. Over the past two decades, several methods for chemical or thermal tumor destruction have been clinically tested. Among these methods, radiofreq...

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Bibliographic Details
Published in:Abdominal imaging 2009-09, Vol.34 (5), p.547-556
Main Authors: Lencioni, Riccardo, Crocetti, Laura, Pina, Maria Clotilde Della, Cioni, Dania
Format: Article
Language:English
Subjects:
Carcinoma, Hepatocellular - pathology
Carcinoma, Hepatocellular - surgery
Catheter Ablation - methods
Colorectal Neoplasms - secondary
Colorectal Neoplasms - surgery
Gastroenterology
Hepatology
Humans
Imaging
Liver Neoplasms - pathology
Liver Neoplasms - surgery
Medicine
Medicine & Public Health
Patient Selection
Radiography, Interventional
Radiology
Ultrasonography, Interventional
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Summary:The development of image-guided percutaneous techniques for local tumor ablation has been one of the major advances in the treatment of liver malignancies. Over the past two decades, several methods for chemical or thermal tumor destruction have been clinically tested. Among these methods, radiofrequency (RF) ablation is currently established as the primary ablative modality at most institutions. RF ablation is accepted as the best therapeutic choice for patients with early-stage hepatocellular carcinoma (HCC) when liver transplantation or surgical resection are not suitable options. In addition, RF ablation is emerging as a viable alternate to surgery for inoperable patients with limited hepatic metastatic disease, especially from colorectal cancer. Several series have shown that RF ablation can result in complete tumor eradication in properly selected candidates, and have provided indirect evidence that the treatment improves survival. In this article, we review technique, indications, and clinical results of percutaneous RF ablation in the treatment of HCC and colorectal hepatic metastases.
ISSN:0942-8925
2366-004X
1432-0509
2366-0058
DOI:10.1007/s00261-008-9479-2