Thulium laser enucleation of the prostate (ThuLEP): transurethral anatomical prostatectomy with laser support. Introduction of a novel technique for the treatment of benign prostatic obstruction

• Published in: World journal of urology 2010-02, Vol.28 (1), p.45-51
• Main Authors: Herrmann, Thomas R. W., Bach, T., Imkamp, F., Georgiou, A., Burchardt, M., Oelke, M., Gross, A. J.
• Format: Article
• Language: English
• Subjects: Humans; Laser Therapy; Male; Medicine; Medicine & Public Health; Nephrology; Oncology; Prostatic Hyperplasia - complications; Prostatic Hyperplasia - surgery; Prostatism - etiology; Prostatism - surgery; Thulium - therapeutic use; Topic Paper; Transurethral Resection of Prostate - methods; Urology
• ISSN: 0724-4983; 1433-8726
• DOI: 10.1007/s00345-009-0503-0

Background Transurethral removal of prostatic tissue is the treatment choice for benign prostatic enlargement and benign prostatic obstruction. Urodynamic results are directly linked to the amount of removed tissue which, however, is directly associated with intra- and postoperative morbidity. Transurethral laser operations of the prostate offer the advantage of decreased bleeding complications and the possibility to treat patients with bleeding disorders or anticoagulative treatment. The aim of the article is to present a novel technique of complete transurethral removal of the transition zone (enucleation) with the support of the Thulium laser to combine complete anatomical enucleation and maximum urodynamic efficacy with minimal side-effects. Materials and methods We present five distinct surgical steps for transurethral complete removal of the transition zone of the prostate (Thulium laser enucleation of the prostate, ThuLEP). Surgical steps are presented in chronological order with the help of intraoperative pictures. Laser energy of 70–90 W is only used for the incision at the verumontanum and bladder neck for removal of the middle lobe, whereas laser energy of 30 W was only used for coagulation of small vessel crossing the surgical capsule towards the transition zone and bladder neck for dissection of the lateral lobes. The lobes themselves are liberated by blunt dissection. Conclusions ThuLEP offers complete removal of the transition zone no matter what prostatic size. The techniques combine maximum efficacy with minimal side-effects. Clinical results comparing ThuLEP with open prostatectomy or transurethral resection are awaited.