Ultrasonographic diagnosis of fetal structural abnormalities in prenatal screening at 11-14 weeks

The aim of the study was to determine the detection rate of structural abnormalities at the 11-14 week ultrasound examination as a part of two-stage screening process in low-risk pregnancies. A total of 1085 consecutive low-risk pregnant women participated in screening by two-stage ultrasonography f...

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Bibliographic Details
Published in:Diagnostic and interventional radiology (Ankara, Turkey) Turkey), 2009-09, Vol.15 (3), p.221-225
Main Authors: Oztekin, Ozgür, Oztekin, Deniz, Tinar, Sivekar, Adibelli, Zehra
Format: Article
Language:English
Subjects:
Abortion, Induced
Chromosome Aberrations - embryology
Female
Hernia, Umbilical - diagnostic imaging
Hernia, Umbilical - embryology
Holoprosencephaly - diagnostic imaging
Holoprosencephaly - embryology
Humans
Karyotyping
Predictive Value of Tests
Pregnancy
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Retrospective Studies
Sensitivity and Specificity
Ultrasonography, Prenatal
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Summary:The aim of the study was to determine the detection rate of structural abnormalities at the 11-14 week ultrasound examination as a part of two-stage screening process in low-risk pregnancies. A total of 1085 consecutive low-risk pregnant women participated in screening by two-stage ultrasonography for the estimation of the sensitivity of the first and second trimester ultrasound scans in the detection of major anomalies as a part of routine screening. Of 1085 pregnancies, 21 (1.93%) fetuses had at least one major structural defect considered detectable by routine ultrasound screening; 14 (1.29%) were identified at early screening and an additional 5 (0.47%) at late screening. Two abnormalities were not detected prenatally, and data were obtained from the patients after delivery. The majority of fetal structural abnormalities can be detected by sonographic screening at 11-14 weeks, but detailed fetal anatomic survey performed at 18-22 weeks should not be abandoned.
ISSN:1305-3825
1305-3612