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Comparative therapeutic effect of moxidectin, doramectin and ivermectin on psoroptes mites infestation in buffalo (Bubalus bubalis)
The aim of the present study was to carry out comparative therapeutic effect of moxidectin pour on, doramectin and ivermectin on psoroptes infestation in buffalo. A total of 318 buffalo in 77 small scale herds suspected to have mange mites were examined clinically and parasitologically. Fifty-three...
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Published in: | Tropical animal health and production 2009-10, Vol.41 (7), p.1505-1511 |
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description | The aim of the present study was to carry out comparative therapeutic effect of moxidectin pour on, doramectin and ivermectin on psoroptes infestation in buffalo. A total of 318 buffalo in 77 small scale herds suspected to have mange mites were examined clinically and parasitologically. Fifty-three (16.66%) buffalo in 25 herds were recorded to be infested; 51 (16.35%) with psoroptic mites, and two (0.31%) with chorioptic mites. Buffalo with psoroptic mites were randomly allocated into three groups (17 buffalo each). First group was treated with moxidectin pour on at a dose rate of 0.5 mg kg⁻¹. The second group received doramectin (200 µg kg⁻¹ twice subcutaneously, 14 days apart). The third group received ivermectin (200 µg kg⁻¹ twice subcutaneously, 14 days apart). Adjunct to each drug, deltamethrin was applied to the surrounding environment twice at a two week interval. Treatment outcomes of 51 buffalo with psoroptic mites showed that moxidectin pour on and doramectin had a significant higher effect on mite count reduction (MANOVA, P |
doi_str_mv | 10.1007/s11250-009-9340-9 |
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A total of 318 buffalo in 77 small scale herds suspected to have mange mites were examined clinically and parasitologically. Fifty-three (16.66%) buffalo in 25 herds were recorded to be infested; 51 (16.35%) with psoroptic mites, and two (0.31%) with chorioptic mites. Buffalo with psoroptic mites were randomly allocated into three groups (17 buffalo each). First group was treated with moxidectin pour on at a dose rate of 0.5 mg kg⁻¹. The second group received doramectin (200 µg kg⁻¹ twice subcutaneously, 14 days apart). The third group received ivermectin (200 µg kg⁻¹ twice subcutaneously, 14 days apart). Adjunct to each drug, deltamethrin was applied to the surrounding environment twice at a two week interval. Treatment outcomes of 51 buffalo with psoroptic mites showed that moxidectin pour on and doramectin had a significant higher effect on mite count reduction (MANOVA, P < 0.01; Walks, Lambda, P < 0.01) and clinical sum scores (MANOVA, P < 0.05; Walks, Lambda, P < 0.05) compared with injectible ivermectin. On clinical level, the number of clinically recovered buffalo in moxidectin and doramectin treated groups was significantly (P < 0.05) higher than that of ivermectin treated group. The result of the present study indicated that psoroptic mites are the main cause of mange in buffalo in Lower Egypt. This is the first report that describes the effect of moxidectin in buffalo. Moxidectin is a good alternative and easily applied drug for treatment of psoroptes infestation in buffalo.</description><identifier>ISSN: 0049-4747</identifier><identifier>EISSN: 1573-7438</identifier><identifier>DOI: 10.1007/s11250-009-9340-9</identifier><identifier>PMID: 19347598</identifier><language>eng</language><publisher>Dordrecht: Dordrecht : Springer Netherlands</publisher><subject>Analysis of Variance ; Animals ; Antiparasitic Agents - pharmacology ; Antiparasitic Agents - therapeutic use ; Biomedical and Life Sciences ; Bubalus bubalis ; Buffaloes ; Deltamethrin ; Egypt ; Ivermectin - analogs & derivatives ; Ivermectin - pharmacology ; Ivermectin - therapeutic use ; Life Sciences ; Macrolides - pharmacology ; Macrolides - therapeutic use ; Mite Infestations - drug therapy ; Mite Infestations - veterinary ; Mites ; Nitriles ; Original Paper ; Psoroptes ; Psoroptidae - drug effects ; Pyrethrins ; Veterinary Medicine/Veterinary Science ; Zoology</subject><ispartof>Tropical animal health and production, 2009-10, Vol.41 (7), p.1505-1511</ispartof><rights>Springer Science+Business Media B.V. 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c491t-6bd98abcbbc0257f816c7d49d84205e755cf77e43fcfe7c3a5ace36ecad588b83</citedby><cites>FETCH-LOGICAL-c491t-6bd98abcbbc0257f816c7d49d84205e755cf77e43fcfe7c3a5ace36ecad588b83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19347598$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>El-Khodery, Sabry A</creatorcontrib><creatorcontrib>Ishii, Mitsu</creatorcontrib><creatorcontrib>Osman, Salama A</creatorcontrib><creatorcontrib>Al-Gaabary, Magdy H</creatorcontrib><title>Comparative therapeutic effect of moxidectin, doramectin and ivermectin on psoroptes mites infestation in buffalo (Bubalus bubalis)</title><title>Tropical animal health and production</title><addtitle>Trop Anim Health Prod</addtitle><addtitle>Trop Anim Health Prod</addtitle><description>The aim of the present study was to carry out comparative therapeutic effect of moxidectin pour on, doramectin and ivermectin on psoroptes infestation in buffalo. A total of 318 buffalo in 77 small scale herds suspected to have mange mites were examined clinically and parasitologically. Fifty-three (16.66%) buffalo in 25 herds were recorded to be infested; 51 (16.35%) with psoroptic mites, and two (0.31%) with chorioptic mites. Buffalo with psoroptic mites were randomly allocated into three groups (17 buffalo each). First group was treated with moxidectin pour on at a dose rate of 0.5 mg kg⁻¹. The second group received doramectin (200 µg kg⁻¹ twice subcutaneously, 14 days apart). The third group received ivermectin (200 µg kg⁻¹ twice subcutaneously, 14 days apart). Adjunct to each drug, deltamethrin was applied to the surrounding environment twice at a two week interval. Treatment outcomes of 51 buffalo with psoroptic mites showed that moxidectin pour on and doramectin had a significant higher effect on mite count reduction (MANOVA, P < 0.01; Walks, Lambda, P < 0.01) and clinical sum scores (MANOVA, P < 0.05; Walks, Lambda, P < 0.05) compared with injectible ivermectin. On clinical level, the number of clinically recovered buffalo in moxidectin and doramectin treated groups was significantly (P < 0.05) higher than that of ivermectin treated group. The result of the present study indicated that psoroptic mites are the main cause of mange in buffalo in Lower Egypt. This is the first report that describes the effect of moxidectin in buffalo. Moxidectin is a good alternative and easily applied drug for treatment of psoroptes infestation in buffalo.</description><subject>Analysis of Variance</subject><subject>Animals</subject><subject>Antiparasitic Agents - pharmacology</subject><subject>Antiparasitic Agents - therapeutic use</subject><subject>Biomedical and Life Sciences</subject><subject>Bubalus bubalis</subject><subject>Buffaloes</subject><subject>Deltamethrin</subject><subject>Egypt</subject><subject>Ivermectin - analogs & derivatives</subject><subject>Ivermectin - pharmacology</subject><subject>Ivermectin - therapeutic use</subject><subject>Life Sciences</subject><subject>Macrolides - pharmacology</subject><subject>Macrolides - therapeutic use</subject><subject>Mite Infestations - drug therapy</subject><subject>Mite Infestations - veterinary</subject><subject>Mites</subject><subject>Nitriles</subject><subject>Original Paper</subject><subject>Psoroptes</subject><subject>Psoroptidae - drug effects</subject><subject>Pyrethrins</subject><subject>Veterinary Medicine/Veterinary Science</subject><subject>Zoology</subject><issn>0049-4747</issn><issn>1573-7438</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNp9kU1v1DAQhi0EosvCD-ACFgcoEgE7_j7CilKkShygZ8tx7OJqE6d2gsqZP84sWakSh15mxp7nHX-8CD2n5D0lRH2olLaCNISYxjBOGvMAbahQrFGc6YdoQwg3DVdcnaAntV4TAiotH6MTCrgSRm_Qn10eJlfcnH4FPP8MxU1hmZPHIcbgZ5wjHvJt6qFO4zvc5-KGfzV2Y49BVI7LPOKp5pKnOVQ8pENMYwx1htHQA6JbYnT7jE8_LZ3bLxU2IKf69il6BI0anh3zFl2eff6xO28uvn35uvt40Xhu6NzIrjfadb7rPGmFippKr3pues1bIoISwkelAmfRx6A8c8L5wGTwrhdad5pt0Zt17lTyzQJXs0OqPuz3bgx5qVbBH8qWsAP5-l6ypa3S1EgAX_0HXueljPAK2youleCKAERXyJdcawnRTiUNrvy2lNiDkXY10oKR9mAkhC16cRy8dEPo7xRH5wBoV6BCa7wK5e7k-6a-XEXRZeuuSqr28ntLKCNUaiklZX8BI-20iw</recordid><startdate>20091001</startdate><enddate>20091001</enddate><creator>El-Khodery, Sabry A</creator><creator>Ishii, Mitsu</creator><creator>Osman, Salama A</creator><creator>Al-Gaabary, Magdy H</creator><general>Dordrecht : Springer Netherlands</general><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7U7</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7SS</scope><scope>7X8</scope></search><sort><creationdate>20091001</creationdate><title>Comparative therapeutic effect of moxidectin, doramectin and ivermectin on psoroptes mites infestation in buffalo (Bubalus bubalis)</title><author>El-Khodery, Sabry A ; Ishii, Mitsu ; Osman, Salama A ; Al-Gaabary, Magdy H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c491t-6bd98abcbbc0257f816c7d49d84205e755cf77e43fcfe7c3a5ace36ecad588b83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Analysis of Variance</topic><topic>Animals</topic><topic>Antiparasitic Agents - pharmacology</topic><topic>Antiparasitic Agents - therapeutic use</topic><topic>Biomedical and Life Sciences</topic><topic>Bubalus bubalis</topic><topic>Buffaloes</topic><topic>Deltamethrin</topic><topic>Egypt</topic><topic>Ivermectin - analogs & derivatives</topic><topic>Ivermectin - pharmacology</topic><topic>Ivermectin - therapeutic use</topic><topic>Life Sciences</topic><topic>Macrolides - pharmacology</topic><topic>Macrolides - therapeutic use</topic><topic>Mite Infestations - drug therapy</topic><topic>Mite Infestations - veterinary</topic><topic>Mites</topic><topic>Nitriles</topic><topic>Original Paper</topic><topic>Psoroptes</topic><topic>Psoroptidae - drug effects</topic><topic>Pyrethrins</topic><topic>Veterinary Medicine/Veterinary Science</topic><topic>Zoology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>El-Khodery, Sabry A</creatorcontrib><creatorcontrib>Ishii, Mitsu</creatorcontrib><creatorcontrib>Osman, Salama A</creatorcontrib><creatorcontrib>Al-Gaabary, Magdy H</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Entomology Abstracts (Full archive)</collection><collection>MEDLINE - Academic</collection><jtitle>Tropical animal health and production</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>El-Khodery, Sabry A</au><au>Ishii, Mitsu</au><au>Osman, Salama A</au><au>Al-Gaabary, Magdy H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative therapeutic effect of moxidectin, doramectin and ivermectin on psoroptes mites infestation in buffalo (Bubalus bubalis)</atitle><jtitle>Tropical animal health and production</jtitle><stitle>Trop Anim Health Prod</stitle><addtitle>Trop Anim Health Prod</addtitle><date>2009-10-01</date><risdate>2009</risdate><volume>41</volume><issue>7</issue><spage>1505</spage><epage>1511</epage><pages>1505-1511</pages><issn>0049-4747</issn><eissn>1573-7438</eissn><abstract>The aim of the present study was to carry out comparative therapeutic effect of moxidectin pour on, doramectin and ivermectin on psoroptes infestation in buffalo. A total of 318 buffalo in 77 small scale herds suspected to have mange mites were examined clinically and parasitologically. Fifty-three (16.66%) buffalo in 25 herds were recorded to be infested; 51 (16.35%) with psoroptic mites, and two (0.31%) with chorioptic mites. Buffalo with psoroptic mites were randomly allocated into three groups (17 buffalo each). First group was treated with moxidectin pour on at a dose rate of 0.5 mg kg⁻¹. The second group received doramectin (200 µg kg⁻¹ twice subcutaneously, 14 days apart). The third group received ivermectin (200 µg kg⁻¹ twice subcutaneously, 14 days apart). Adjunct to each drug, deltamethrin was applied to the surrounding environment twice at a two week interval. Treatment outcomes of 51 buffalo with psoroptic mites showed that moxidectin pour on and doramectin had a significant higher effect on mite count reduction (MANOVA, P < 0.01; Walks, Lambda, P < 0.01) and clinical sum scores (MANOVA, P < 0.05; Walks, Lambda, P < 0.05) compared with injectible ivermectin. On clinical level, the number of clinically recovered buffalo in moxidectin and doramectin treated groups was significantly (P < 0.05) higher than that of ivermectin treated group. The result of the present study indicated that psoroptic mites are the main cause of mange in buffalo in Lower Egypt. This is the first report that describes the effect of moxidectin in buffalo. Moxidectin is a good alternative and easily applied drug for treatment of psoroptes infestation in buffalo.</abstract><cop>Dordrecht</cop><pub>Dordrecht : Springer Netherlands</pub><pmid>19347598</pmid><doi>10.1007/s11250-009-9340-9</doi><tpages>7</tpages></addata></record> |
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subjects | Analysis of Variance Animals Antiparasitic Agents - pharmacology Antiparasitic Agents - therapeutic use Biomedical and Life Sciences Bubalus bubalis Buffaloes Deltamethrin Egypt Ivermectin - analogs & derivatives Ivermectin - pharmacology Ivermectin - therapeutic use Life Sciences Macrolides - pharmacology Macrolides - therapeutic use Mite Infestations - drug therapy Mite Infestations - veterinary Mites Nitriles Original Paper Psoroptes Psoroptidae - drug effects Pyrethrins Veterinary Medicine/Veterinary Science Zoology |
title | Comparative therapeutic effect of moxidectin, doramectin and ivermectin on psoroptes mites infestation in buffalo (Bubalus bubalis) |
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