High prevalence of Chlamydia pneumoniae antibodies in white-coat hypertensives

Previous studies have linked essential sustained hypertension with Chlamydia pneumoniae ( C. pneumoniae) and changes in intima-media thickness (IMT) of carotid arteries. The aim of this study was to examine if similar associations exist in subjects with white-coat hypertension. C. pneumoniae IgA and...

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Bibliographic Details
Published in:Atherosclerosis 2003-04, Vol.167 (2), p.231-235
Main Authors: Pitiriga, Vassiliki C., Kotsis, Vasilios T., Papamichail, Christos M., Alexandrou, Maria-Eleni K., Lekakis, John P., Kokolakis, Nikos, Petrocheilou-Paschou, Vassiliky D., Zakopoulos, Nikos A.
Format: Article
Language:English
Subjects:
Adult
Aged
Antibodies, Bacterial - analysis
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Blood Pressure Determination - methods
Blood Pressure Monitoring, Ambulatory
C. pneumoniae infection
Cardiology. Vascular system
Carotid Arteries - diagnostic imaging
Carotid Arteries - physiopathology
Case-Control Studies
Chlamydophila Infections - diagnosis
Chlamydophila Infections - epidemiology
Chlamydophila pneumoniae - immunology
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Female
Humans
Hypertension - diagnosis
Hypertension - epidemiology
Hypertension - immunology
Intima-media thickness
Male
Medical sciences
Middle Aged
Prevalence
Probability
Reference Values
Risk Factors
Sampling Studies
Sensitivity and Specificity
Severity of Illness Index
Tunica Intima - microbiology
Tunica Intima - pathology
Ultrasonography, Doppler
White-coat hypertension
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Summary:Previous studies have linked essential sustained hypertension with Chlamydia pneumoniae ( C. pneumoniae) and changes in intima-media thickness (IMT) of carotid arteries. The aim of this study was to examine if similar associations exist in subjects with white-coat hypertension. C. pneumoniae IgA and IgG antibody titers were measured in 125 patients with white-coat hypertension and 54 normotensives. All participants underwent a 24 h ambulatory blood pressure (BP) monitoring, clinic BP readings and common-internal carotid artery IMT measurements. Seventy subjects of the white-coat group (56%) and 15 of the control group (27.8%) had IgG titers ≥80 (crosstabs; P
ISSN:0021-9150
1879-1484
DOI:10.1016/S0021-9150(02)00426-4