Quantitative Detection of Bioassays with a Low-Cost Image-Sensor Array for Integrated Microsystems

Portable assay systems require inexpensive detectors that can be integrated with microfluidic sample handling. Now a mass‐produced digital‐camera sensor has been interfaced with different lab‐on‐a‐chip architectures to image nanoliter reagent droplets and for quantitative photometry of colorimetric...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie (International ed.) 2009-09, Vol.48 (41), p.7649-7654
Main Authors: Vykoukal, Daynene M, Stone, Gregory P, Gascoyne, Peter R.C, Alt, Eckhard U, Vykoukal, Jody
Format: Article
Language:English
Subjects:
analytical methods
Animals
Biological Assay - instrumentation
Biological Assay - methods
Biosensing Techniques - instrumentation
Biosensing Techniques - methods
colorimetry
droplets
Electrochemistry - instrumentation
Electrochemistry - methods
Humans
luminescence
Microfluidics
Point-of-Care Systems
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Portable assay systems require inexpensive detectors that can be integrated with microfluidic sample handling. Now a mass‐produced digital‐camera sensor has been interfaced with different lab‐on‐a‐chip architectures to image nanoliter reagent droplets and for quantitative photometry of colorimetric and bioluminescence assays (see contact images of the fluid‐handling electrode array (right), and colorimetric (top) and bioluminescent samples (bottom)).
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200901814