The Role of “Fatty Pancreas” and of BMI in the Occurrence of Pancreatic Fistula After Pancreaticoduodenectomy

Introduction Pancreatic fistula (PF) after pancreaticoduodenectomy (PD) is still a serious complication. We hypothesized that the amount of fatty tissue in the pancreatic parenchyma could be associated with the occurrence of PF after PD with pancreatogastrostomy. Material and methods From January 20...

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Bibliographic Details
Published in:Journal of gastrointestinal surgery 2009-10, Vol.13 (10), p.1845-1851
Main Authors: Rosso, Edoardo, Casnedi, Selenia, Pessaux, Patrick, Oussoultzoglou, Elie, Panaro, Fabrizio, Mahfud, Mahfud, Jaeck, Daniel, Bachellier, Philippe
Format: Article
Language:English
Subjects:
Adipose Tissue - pathology
Adult
Aged
Aged, 80 and over
Body Mass Index
Female
Gastroenterology
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Mortality
Original Article
Pancreas
Pancreas - pathology
Pancreatic Diseases - surgery
Pancreatic Fistula - etiology
Pancreatic Fistula - pathology
Pancreaticoduodenectomy - adverse effects
Retrospective Studies
Surgery
Young Adult
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Summary:Introduction Pancreatic fistula (PF) after pancreaticoduodenectomy (PD) is still a serious complication. We hypothesized that the amount of fatty tissue in the pancreatic parenchyma could be associated with the occurrence of PF after PD with pancreatogastrostomy. Material and methods From January 2004 to December 2006, 111 consecutive patients underwent PD with pancreatogastrostomy. The microscopic amount of fatty tissue in the pancreas was evaluated. Results The morbidity and mortality rates were 35.1% and 1.8%, respectively. PF occurred in 10.8% ( n  = 12). PF was of grade A in nine, grade B in two, and grade C in one patient. Univariate analysis showed that a body mass index (BMI) > 25 ( P  = 0.035), a soft pancreatic parenchyma ( P  = 
ISSN:1091-255X
1873-4626
DOI:10.1007/s11605-009-0974-8