Multinational Study of Reliability and Validity of the King's Health Questionnaire in Patients with Overactive Bladder

Objective: Overactive bladder (OAB) has substantial impact on health-related quality of life (HRQoL). The purpose of this research was to evaluate the psychometric properties of the King's Health Questionnaire (KHQ). Methods: The KHQ (n = 1284) was administered at baseline and 12 weeks post-tre...

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Bibliographic Details
Published in:Quality of life research 2003-06, Vol.12 (4), p.427-442
Main Authors: Pat Ray Reese, Andreas M. Pleil, Okano, Gary J., Con J. Kelleher
Format: Article
Language:English
Subjects:
Aged
Clinical trials
Correlations
Energy
Female
Humans
Male
Middle Aged
Overactive bladder
Personal relationships
Placebos
Psychometrics
Quality of Life
Quantitative psychology
Questionnaires
Sickness Impact Profile
Surveys and Questionnaires - standards
Urinary bladder
Urinary incontinence
Urination Disorders
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Summary:Objective: Overactive bladder (OAB) has substantial impact on health-related quality of life (HRQoL). The purpose of this research was to evaluate the psychometric properties of the King's Health Questionnaire (KHQ). Methods: The KHQ (n = 1284) was administered at baseline and 12 weeks post-treatment in a multinational, double-blind, randomized clinical trial of tolterodine for treatment of OAB. Country-specific psychometric analyses of HRQoL instruments were performed. Countries demonstrating marginal psychometric properties on the KHQ were pooled with same-language countries, re-evaluated, and aggregate analysis performed on the pooled data. Results: Internal consistency of the KHQ was high, item characteristics were good, most assumptions of summed scales were met, and it is externally valid and consistent. Few problems with the KHQ were noted although the performance of the personal relationships domain was complicated by the 'not applicable' response category. Conclusions: Psychometric testing supports the reliability and validity of the KHQ as an OAB-specific measure of HRQoL.
ISSN:0962-9343
1573-2649
DOI:10.1023/A:1023422208910