Langerhans cell histiocytosis revealed by painful hip: A case report

Abstract Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal...

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Bibliographic Details
Published in:Joint, bone, spine : revue du rhumatisme bone, spine : revue du rhumatisme, 2009-10, Vol.76 (5), p.565-566
Main Authors: Sabeur, Hammami, Chebil, B. Meriem, Karim, B. Ameur, Samir, Hadded, Leila, Ghédira, Chiraz, Hafsa, Slaheddine, Chouchane, Néji, Guediche Mohamed
Format: Article
Language:English
Subjects:
Adrenal Cortex Hormones - therapeutic use
Arthralgia
Child
Female
Femur - diagnostic imaging
Femur - pathology
Functional Laterality
Hip
Hip Joint - diagnostic imaging
Hip Joint - pathology
Histiocytosis, Langerhans-Cell - diagnostic imaging
Histiocytosis, Langerhans-Cell - drug therapy
Histiocytosis, Langerhans-Cell - pathology
Humans
Infant
Internal Medicine
Langerhans cell histiocytosis
Magnetic Resonance Imaging
Osteosclerosis - diagnostic imaging
Otitis - diagnosis
Pain - etiology
Radiography
Rheumatology
Treatment Outcome
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Summary:Abstract Langerhans cell histiocytosis is a rare disease in childhood. It has a very polymorphous clinical expression, ranging from a single bony disease to a multisystemic disease involving vital organs. Prognosis has been improved by use of chemotherapy. We report a 2-year-old girl with multifocal Langerhans cell histiocytosis of bone and skin, revealed by a pain of the left hip and a limp trailing from 2 months. The diagnosis has been established by histological exam. The patient received chemotherapy and steroids. Outcome was favourable over 6-month follow-up. Trailing limp should evoke diagnosis of Langerhans cell histiocytosis. Skin biopsy should be preferred to a bone biopsy because of its safety.
ISSN:1297-319X
1778-7254
DOI:10.1016/j.jbspin.2009.01.014