Mycobacterium Chelonae Infections Involving the Head and Neck

Objectives: We describe the manifestations, diagnosis, and treatment of rare head and neck infections caused by Mycobacterium chelonae, including a case of maxillary osteitis and skull base osteomyelitis. Methods: A comprehensive literature search (MEDLINE from 1951; BIOSIS from 1969; EMBASE from 19...

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Bibliographic Details
Published in:Annals of otology, rhinology & laryngology rhinology & laryngology, 2009-10, Vol.118 (10), p.714-720
Main Authors: Mullin, David, Jothi, Sumana, Healy, David
Format: Article
Language:English
Subjects:
Abscess - microbiology
Aged
Anti-Bacterial Agents - administration & dosage
Bacterial arthritis and osteitis
Bacterial diseases
Biological and medical sciences
Clarithromycin - administration & dosage
Combined Modality Therapy
Debridement
Female
Human bacterial diseases
Humans
Infectious diseases
Maxillary Sinus
Medical sciences
Middle Aged
Mycobacterium chelonae
Mycobacterium Infections, Nontuberculous - drug therapy
Mycobacterium Infections, Nontuberculous - surgery
Mycobacterium Infections, Nontuberculous - therapy
Osteitis - microbiology
Osteitis - therapy
Osteomyelitis - microbiology
Otorhinolaryngology. Stomatology
Paranasal Sinus Diseases - microbiology
Paranasal Sinus Diseases - therapy
Reconstructive Surgical Procedures - methods
Skull Base - microbiology
Tuberculosis and atypical mycobacterial infections
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Summary:Objectives: We describe the manifestations, diagnosis, and treatment of rare head and neck infections caused by Mycobacterium chelonae, including a case of maxillary osteitis and skull base osteomyelitis. Methods: A comprehensive literature search (MEDLINE from 1951; BIOSIS from 1969; EMBASE from 1980) was performed for the presentation, diagnostic evaluation, and outcomes of patients with M chelonae infections. Results: We report 4 cases of M chelonae infection, including a nasal abscess following septorhinoplasty with a cartilaginous graft, a case of chronic unilateral nasal obstruction, and the first reported cases of skull base osteomyelitis and maxillary osteitis secondary to M chelonae. All 4 cases involved immunocompetent individuals. Conclusions: Mycobacterium chelonae should be considered in cases of abscesses that persist despite broad-spectrum intravenous antibiotics, and in cases of maxillary sinusitis with bony involvement that do not respond to traditional treatment methods.
ISSN:0003-4894
1943-572X
DOI:10.1177/000348940911801006