Analysis of sulfonamides in environmental water samples based on magnetic mixed hemimicelles solid-phase extraction coupled with HPLC–UV detection

• Published in: Chemosphere (Oxford) 2009-11, Vol.77 (10), p.1306-1312
• Main Authors: Sun, Lei, Chen, Ligang, Sun, Xin, Du, Xiaobo, Yue, Yanshan, He, Dongqing, Xu, Haoyan, Zeng, Qinglei, Wang, Hui, Ding, Lan
• Format: Article
• Language: English
• Subjects: Adsorption; Air. Soil. Water. Waste. Feeding; Animal, plant and microbial ecology; Applied ecology; Applied sciences; Biological and medical sciences; Cations; Chromatography, High Pressure Liquid - methods; Ecotoxicology, biological effects of pollution; Environment. Living conditions; Environmental water samples; Exact sciences and technology; Extraction; Fe 3O 4 nanoparticles; Ferric Compounds - chemistry; Fundamental and applied biological sciences. Psychology; Hydrogen-Ion Concentration; Magnetic mixed hemimicelles solid-phase extraction; Magnetics; Medical sciences; Metal Nanoparticles - chemistry; Micelles; Pollution; Public health. Hygiene; Public health. Hygiene-occupational medicine; SAS; Solid Phase Extraction - methods; Spectrophotometry, Ultraviolet - methods; Standard deviation; Sulfonamides; Sulfonamides - analysis; Sulfonamides - chemistry; Sulfonamides - isolation & purification; Surface chemistry; Surface-Active Agents - chemistry; Surfactants; Water Pollutants, Chemical - analysis; Water Pollutants, Chemical - chemistry; Water Pollutants, Chemical - isolation & purification
• ISSN: 0045-6535; 1879-1298
• DOI: 10.1016/j.chemosphere.2009.09.049

The magnetic mixed hemimicelles solid-phase extraction (MMHSPE), based on the adsorption of cation surfactant octadecyltrimethylammonium bromide (OTMABr) onto magnetite nanoparticles (Fe 3O 4 NPs) to form mixed hemimicelles, was proposed for the preconcentration of several sulfonamides (SAs) compounds including sulfamethoxazole (SMX), sulfamethoxydiazine (SMD), sulfadimethoxine (SDM) and sulfaquinoxaline (SQX) from environmental water samples. This method avoided the time-consuming column-passing process of loading large volume samples in traditional SPE through the rapid isolation of OTMABr-coated Fe 3O 4 NPs with an adscititious magnet. Mixed hemimicelles formed on the surface of Fe 3O 4 NPs by OTMABr showed great adsorptive tendency towards analytes. The OTMABr-coated Fe 3O 4 NPs adsorbents were easy to be prepared, low cost and environmentally friendly. A comprehensive study on the adsorption conditions such as the amount of the surfactant, the solution pH, the desorption condition and the maximum extraction sample volume were optimized. A concentration factor of 1000 was achieved by the extraction of 500 mL of environmental water samples using MMHSPE. Detection limits obtained for SMX, SMD, SDM and SQX were 0.026, 0.024, 0.033 and 0.030 μg L −1, respectively. Good recoveries (70–102%) with low relative standard deviations (1–6%) were achieved in analyzing spiked water samples. Low concentration of SQX was found in hospital primary and final sewage effluent sample.