Changes in the Content of Protein and Lipid Oxidative Modification Products in Tumor Tissue at Different Stages of Lung Cancer

The content of LPO products (conjugated dienes, MDA) and products of oxidative modification of proteins (protein carbonyl derivatives) is reduced in tumor tissue in comparison with normal tissue and varies depending on the disease stage.

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2009-05, Vol.147 (5), p.630-631
Main Authors: Belonogov, R. N, Titova, N. M, Lapeshin, P. V, Ivanova, Yu. R, Shevtsova, A. O, Pokrovskii, A. A
Format: Article
Language:English
Subjects:
Adult
Biomedical and Life Sciences
Biomedicine
Cell Biology
Humans
Internal Medicine
Laboratory Medicine
Lipid Metabolism - physiology
lipid peroxidation
Lipid Peroxidation - physiology
Lung cancer
lung neoplasms
Lung Neoplasms - metabolism
Lung Neoplasms - pathology
Male
Middle Aged
Neoplasm Staging
Oncology
Oxidation-Reduction
oxidative modification of proteins
Pathology
Protein Carbonylation
Proteins - metabolism
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Description
Summary:The content of LPO products (conjugated dienes, MDA) and products of oxidative modification of proteins (protein carbonyl derivatives) is reduced in tumor tissue in comparison with normal tissue and varies depending on the disease stage.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-009-0565-4