Studying the Copy Number of Ribosomal Protein L7/L12

Studying the copy number of ribosomal protein L7/L12 was performed using monoclonal antibody 3G9 to the linear epitope on the C-terminal domain of this protein from Escherichia coli. Immunohistochemical study showed that Agrobacterium tumefaciens ribosomes include 6 copies of protein L7/L12. Our res...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2009-05, Vol.147 (5), p.587-591
Main Authors: Grebenyuk, E. S, Dokrunova, A. A, Davydov, Ia. I, Tonevitsky, E. A, Tonevitsky, A. G
Format: Article
Language:English
Subjects:
Agrobacterium tumefaciens
Agrobacterium tumefaciens - genetics
Agrobacterium tumefaciens - metabolism
Amino Acid Sequence
Bacterial Proteins - chemistry
Bacterial Proteins - genetics
Bacterial Proteins - metabolism
Biomedical and Life Sciences
Biomedicine
Biophysics and Biochemistry
Cell Biology
copy number
Epitopes - genetics
Escherichia coli
Escherichia coli - genetics
Escherichia coli - metabolism
Evolution, Molecular
Gene Dosage - genetics
Immunohistochemistry
Internal Medicine
Laboratory Medicine
Molecular Sequence Data
monoclonal antibodies
Pathology
Protein Structure, Secondary
ribosomal protein L7/L12
Ribosomal Proteins - chemistry
Ribosomal Proteins - genetics
Ribosomal Proteins - metabolism
Sequence Homology, Amino Acid
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Summary:Studying the copy number of ribosomal protein L7/L12 was performed using monoclonal antibody 3G9 to the linear epitope on the C-terminal domain of this protein from Escherichia coli. Immunohistochemical study showed that Agrobacterium tumefaciens ribosomes include 6 copies of protein L7/L12. Our results suggest that the copy number of this protein has an evolutionary role.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-009-0576-1