Aggressive characteristics of cervical cancer in young women in Taiwan

Abstract Objective To compare the characteristics and prognosis of cervical cancer in young women (under 30 years) with those of older women (over 30 years). Methods A retrospective study of 2443 patients diagnosed with FIGO stage IA–IIA cervical cancer who underwent surgical procedures between Janu...

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Bibliographic Details
Published in:International journal of gynecology and obstetrics 2009-12, Vol.107 (3), p.220-223
Main Authors: Lau, Hei-Yu, Juang, Chi-Mou, Chen, Yi-Jen, Twu, Nae-Fang, Yen, Ming-Shyen, Chao, Kuan-Chong
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Biological and medical sciences
Carcinoma, Squamous Cell - pathology
Cervical adenocarcinoma
Cervical cancer
Dermatology
Disease-Free Survival
Female
Female genital diseases
Gynecology. Andrology. Obstetrics
Humans
Medical sciences
Middle Aged
Neoplasm Metastasis
Neoplasm Recurrence, Local
Neoplasm Staging
Non-squamous cell carcinoma
Obstetrics and Gynecology
Proportional Hazards Models
Retrospective Studies
Taiwan
Tumors
Tumors of the skin and soft tissue. Premalignant lesions
Uterine Cervical Neoplasms - pathology
Young Adult
Young women
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Summary:Abstract Objective To compare the characteristics and prognosis of cervical cancer in young women (under 30 years) with those of older women (over 30 years). Methods A retrospective study of 2443 patients diagnosed with FIGO stage IA–IIA cervical cancer who underwent surgical procedures between January 1983 and December 2007. Results Thirty patients (1.2%) were 30 years or younger. The proportion of non-squamous cell carcinoma was higher in patients 30 years or younger compared with in patients over 30 years (14/30, 46.7% vs 10/30, 33.3%; P = 0.001). A higher rate of parametrial involvement was found in the younger group of patients compared with those over 30 years (10/30, 33.3% vs 289/2413, 12.0%; P = 0.001). Patients under 30 years had a higher rate of distant metastases compared with older patients (60% vs 49.7%; P = 0.036). Conclusions Non-squamous histology, parametrial involvement, a higher rate of distant metastases, and poorer prognosis are more common in women aged 30 or younger with cervical cancer than in older women with the disease.
ISSN:0020-7292
1879-3479
DOI:10.1016/j.ijgo.2009.07.029