Kidney Transplantation in the Context of Renal Replacement Therapy

Kidney transplantation has dramatically evolved from a life-saving yet unproven therapy for patients with renal failure to a mature field that is the preferred treatment for those suffering from ESRD. Patients who receive a transplant experience a 68% lower risk of death compared with those waiting...

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Bibliographic Details
Published in:Clinical journal of the American Society of Nephrology 2009-12, Vol.4 (12), p.2035-2039
Main Author: Pesavento, Todd E
Format: Article
Language:English
Subjects:
Comorbidity
Humans
Kidney Failure, Chronic - mortality
Kidney Failure, Chronic - surgery
Kidney Failure, Chronic - therapy
Kidney Transplantation - mortality
Kidney Transplantation - trends
Renal Replacement Therapy - mortality
Renal Replacement Therapy - trends
Risk Factors
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Summary:Kidney transplantation has dramatically evolved from a life-saving yet unproven therapy for patients with renal failure to a mature field that is the preferred treatment for those suffering from ESRD. Patients who receive a transplant experience a 68% lower risk of death compared with those waiting on dialysis for a transplant. This benefit is afforded to all patient subgroups including the elderly (> or =70 yr), and diabetics, who can gain 11 yr of extra life with transplantation. Prolonged transplant wait times result in a higher risk of death but this can be ameliorated with preemptive transplantation. Future challenges will focus on appropriate organ allocation and addressing long-term renal function and comorbid conditions so patients can enjoy the full benefits of transplantation.
ISSN:1555-9041
1555-905X
DOI:10.2215/CJN.05500809