The development of a microwave fluid-bed processor. I: Construction and qualification of a prototype laboratory unit

The static bed- and planetary-type microwave dryers currently available to process pharmaceutical materials are not designed to use hot-air fluidization for the purpose of maximizing microwave energy inputs and particle drying. To take advantage of the benefits offered by fluidization, a 1-kg Uni-Ga...

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Bibliographic Details
Published in:Pharmaceutical research 1992-11, Vol.9 (11), p.1487-1492
Main Authors: DOELLING, M. K, JONES, D. M, SMITH, R. A, NASH, R. A
Format: Article
Language:English
Subjects:
Biological and medical sciences
Calibration
Desiccation
Drug Compounding - instrumentation
General pharmacology
Medical sciences
Microwaves
Pharmaceutical technology. Pharmaceutical industry
Pharmacology. Drug treatments
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Summary:The static bed- and planetary-type microwave dryers currently available to process pharmaceutical materials are not designed to use hot-air fluidization for the purpose of maximizing microwave energy inputs and particle drying. To take advantage of the benefits offered by fluidization, a 1-kg Uni-Gatt laboratory fluid bed processor was modified to support microwave-assisted fluid bed drying of several representative pharmaceutical granulations. The construction, design features, and validation of this new microwave fluid bed processor are presented.
ISSN:0724-8741
1573-904X
DOI:10.1023/A:1015875300053