Genotyping of rotavirus isolates collected from children less than 5 years of age admitted for diarrhoea at the Yangon Children's Hospital, Myanmar

Abstract Rotavirus positive stool specimens collected from children less than 5-year-old admitted to Yangon Children's Hospital for diarrhoea were analysed for their G and P genotypes. In 2004, rotavirus was detected in 57% of 1004 samples tested with G3 and P[8] being the most common genotypes...

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Bibliographic Details
Published in:Vaccine 2009-11, Vol.27, p.F89-F92
Main Authors: Moe, Kyaw, Thu, Hlaing Myat, Oo, Win Mar, Aye, Khin Mar, Shwe, Thin Thin, Mar, Win, Kirkwood, Carl D
Format: Article
Language:English
Subjects:
Age Distribution
Allergy and Immunology
Child, Preschool
Diarrhea - epidemiology
Diarrhea - virology
Gastroenteritis - epidemiology
Gastroenteritis - virology
Genotype
Genotype distribution
Hospitals, Pediatric
Humans
Incidence
Infant
Molecular Epidemiology
Myanmar - epidemiology
Prevalence
Rotavirus
Rotavirus - genetics
Rotavirus - isolation & purification
Rotavirus Infections - epidemiology
Seasons
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Summary:Abstract Rotavirus positive stool specimens collected from children less than 5-year-old admitted to Yangon Children's Hospital for diarrhoea were analysed for their G and P genotypes. In 2004, rotavirus was detected in 57% of 1004 samples tested with G3 and P[8] being the most common genotypes identified. Corresponding figures in 2005, were 55% of 1175 samples positive for rotavirus with G3 and P[4] genotypes being most common. The most common G and P combinations were G3P[8] and G1P[8], with some unusual combinations (G1P[4], G1P[6] and G3P[4]) also being identified. In Myanmar, ongoing rotavirus surveillance to understand the distribution of G and P genotypes will be important for monitoring the impact of rotavirus vaccines following their introduction into the infant immunization schedule.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2009.08.068