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Cardiovascular risk profile and insulin resistance according body mass index, waist circumference and hypertriglyceridemic waist in adult subjects
Insulin plays a determinant role in the individual metabolic profile. Obesity, the most common cause of insulin resistance (IR), can be diagnosed by body mass index (BMI). Waist circumference (WC), specifically, measures accumulation of abdominal fat. The cardiovascular risk of an individual is stro...
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Published in: | Revista medíca de Chile 2009-09, Vol.137 (9), p.1179-1186 |
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creator | Espinoza Z, Milagros Ruiz F, Nelina Barrios, Emilia Reigosa, Aldo Leal H, Ulises González, Julio César |
description | Insulin plays a determinant role in the individual metabolic profile. Obesity, the most common cause of insulin resistance (IR), can be diagnosed by body mass index (BMI). Waist circumference (WC), specifically, measures accumulation of abdominal fat. The cardiovascular risk of an individual is strongly related to a combination of abdominal obesity with hypertriglyceridemia or hypertriglyceridemic waist (HTW).
To assess the metabolic profile of cardiovascular risk and RI according to BMI, WC and HTW in adult patients.
Weight, height, BMI, blood pressure (BP), WC, HTW, blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides and insulin were assessed and IR calculated by the homeostasis model assessment (HOMA) in 63 females aged 46+/-11 years and 12 males aged 4 7+/- 10 years.
Differences in weight, WC, BP, lipids, glucose, insulin and HOMA, were observed as BMI increased. When patients were grouped according to WC, there were significant differences only in systolic pressure, triglycerides, insulin and HOMA. Individuals with HTW had a more adverse metabolic profile than those without HTW or with only high WC. A multiple regression equation determined that body mass index, total cholesterol and diastolic blood pressure were independent predictors of insulin resistance.
Patients with HTW displayed an unfavorable cardiac risk profile. |
doi_str_mv | 10.4067/S0034-98872009000900006 |
format | article |
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To assess the metabolic profile of cardiovascular risk and RI according to BMI, WC and HTW in adult patients.
Weight, height, BMI, blood pressure (BP), WC, HTW, blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides and insulin were assessed and IR calculated by the homeostasis model assessment (HOMA) in 63 females aged 46+/-11 years and 12 males aged 4 7+/- 10 years.
Differences in weight, WC, BP, lipids, glucose, insulin and HOMA, were observed as BMI increased. When patients were grouped according to WC, there were significant differences only in systolic pressure, triglycerides, insulin and HOMA. Individuals with HTW had a more adverse metabolic profile than those without HTW or with only high WC. A multiple regression equation determined that body mass index, total cholesterol and diastolic blood pressure were independent predictors of insulin resistance.
Patients with HTW displayed an unfavorable cardiac risk profile.</description><identifier>ISSN: 0034-9887</identifier><identifier>DOI: 10.4067/S0034-98872009000900006</identifier><identifier>PMID: 20011958</identifier><language>spa</language><publisher>Chile</publisher><subject>Blood Pressure - physiology ; Body Mass Index ; Cardiovascular Diseases - etiology ; Epidemiologic Methods ; Female ; Humans ; Hypertriglyceridemia - blood ; Hypertriglyceridemia - complications ; Insulin Resistance - physiology ; Lipids - blood ; Male ; Middle Aged ; Risk Assessment - methods ; Risk Factors ; Waist Circumference - physiology</subject><ispartof>Revista medíca de Chile, 2009-09, Vol.137 (9), p.1179-1186</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27915,27916</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20011958$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Espinoza Z, Milagros</creatorcontrib><creatorcontrib>Ruiz F, Nelina</creatorcontrib><creatorcontrib>Barrios, Emilia</creatorcontrib><creatorcontrib>Reigosa, Aldo</creatorcontrib><creatorcontrib>Leal H, Ulises</creatorcontrib><creatorcontrib>González, Julio César</creatorcontrib><title>Cardiovascular risk profile and insulin resistance according body mass index, waist circumference and hypertriglyceridemic waist in adult subjects</title><title>Revista medíca de Chile</title><addtitle>Rev Med Chil</addtitle><description>Insulin plays a determinant role in the individual metabolic profile. Obesity, the most common cause of insulin resistance (IR), can be diagnosed by body mass index (BMI). Waist circumference (WC), specifically, measures accumulation of abdominal fat. The cardiovascular risk of an individual is strongly related to a combination of abdominal obesity with hypertriglyceridemia or hypertriglyceridemic waist (HTW).
To assess the metabolic profile of cardiovascular risk and RI according to BMI, WC and HTW in adult patients.
Weight, height, BMI, blood pressure (BP), WC, HTW, blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides and insulin were assessed and IR calculated by the homeostasis model assessment (HOMA) in 63 females aged 46+/-11 years and 12 males aged 4 7+/- 10 years.
Differences in weight, WC, BP, lipids, glucose, insulin and HOMA, were observed as BMI increased. When patients were grouped according to WC, there were significant differences only in systolic pressure, triglycerides, insulin and HOMA. Individuals with HTW had a more adverse metabolic profile than those without HTW or with only high WC. A multiple regression equation determined that body mass index, total cholesterol and diastolic blood pressure were independent predictors of insulin resistance.
Patients with HTW displayed an unfavorable cardiac risk profile.</description><subject>Blood Pressure - physiology</subject><subject>Body Mass Index</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Epidemiologic Methods</subject><subject>Female</subject><subject>Humans</subject><subject>Hypertriglyceridemia - blood</subject><subject>Hypertriglyceridemia - complications</subject><subject>Insulin Resistance - physiology</subject><subject>Lipids - blood</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Risk Assessment - methods</subject><subject>Risk Factors</subject><subject>Waist Circumference - physiology</subject><issn>0034-9887</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNp90M1OxCAQB3AOGnddfQXlpBerUNpSjmbjV2LiQT03FKYrK_0QitrX8Ikl7urRA5lk5jf_ZEDomJLzjBT84pEQliWiLHlKiCCbR4odNP8bzNC-92tCUl7Qcg_NIqRU5OUcfS2l06Z_l14FKx12xr_iwfWNsYBlp7HpfLCmww688aPsVGwr1celboXrXk-4ld5HpuHzDH_IiLAyToW2AQc_PKa8TAO40ZmVnRQ4o6E1aotjttTBjtiHeg1q9Adot5HWw-G2LtDz9dXT8ja5f7i5W17eJwPldEwEF8DzkqYllZkWggHJ80YJyJkWslZUZ0powlkjQKacFiyveZHpRtSEKyrYAp1ucuO5bwH8WLXGK7BWdtAHX3GWUcE541Ge_CtTSinPRBnh0RaGugVdDc600k3V73-zb2E2hUg</recordid><startdate>200909</startdate><enddate>200909</enddate><creator>Espinoza Z, Milagros</creator><creator>Ruiz F, Nelina</creator><creator>Barrios, Emilia</creator><creator>Reigosa, Aldo</creator><creator>Leal H, Ulises</creator><creator>González, Julio César</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7U1</scope><scope>7U2</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>200909</creationdate><title>Cardiovascular risk profile and insulin resistance according body mass index, waist circumference and hypertriglyceridemic waist in adult subjects</title><author>Espinoza Z, Milagros ; Ruiz F, Nelina ; Barrios, Emilia ; Reigosa, Aldo ; Leal H, Ulises ; González, Julio César</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p171t-979e7581281a4d993e055fc9e53d9abc1d4c9d073f9ea271635b764df9b07c193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2009</creationdate><topic>Blood Pressure - physiology</topic><topic>Body Mass Index</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Epidemiologic Methods</topic><topic>Female</topic><topic>Humans</topic><topic>Hypertriglyceridemia - blood</topic><topic>Hypertriglyceridemia - complications</topic><topic>Insulin Resistance - physiology</topic><topic>Lipids - blood</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Risk Assessment - methods</topic><topic>Risk Factors</topic><topic>Waist Circumference - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Espinoza Z, Milagros</creatorcontrib><creatorcontrib>Ruiz F, Nelina</creatorcontrib><creatorcontrib>Barrios, Emilia</creatorcontrib><creatorcontrib>Reigosa, Aldo</creatorcontrib><creatorcontrib>Leal H, Ulises</creatorcontrib><creatorcontrib>González, Julio César</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>Revista medíca de Chile</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Espinoza Z, Milagros</au><au>Ruiz F, Nelina</au><au>Barrios, Emilia</au><au>Reigosa, Aldo</au><au>Leal H, Ulises</au><au>González, Julio César</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cardiovascular risk profile and insulin resistance according body mass index, waist circumference and hypertriglyceridemic waist in adult subjects</atitle><jtitle>Revista medíca de Chile</jtitle><addtitle>Rev Med Chil</addtitle><date>2009-09</date><risdate>2009</risdate><volume>137</volume><issue>9</issue><spage>1179</spage><epage>1186</epage><pages>1179-1186</pages><issn>0034-9887</issn><abstract>Insulin plays a determinant role in the individual metabolic profile. Obesity, the most common cause of insulin resistance (IR), can be diagnosed by body mass index (BMI). Waist circumference (WC), specifically, measures accumulation of abdominal fat. The cardiovascular risk of an individual is strongly related to a combination of abdominal obesity with hypertriglyceridemia or hypertriglyceridemic waist (HTW).
To assess the metabolic profile of cardiovascular risk and RI according to BMI, WC and HTW in adult patients.
Weight, height, BMI, blood pressure (BP), WC, HTW, blood glucose, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides and insulin were assessed and IR calculated by the homeostasis model assessment (HOMA) in 63 females aged 46+/-11 years and 12 males aged 4 7+/- 10 years.
Differences in weight, WC, BP, lipids, glucose, insulin and HOMA, were observed as BMI increased. When patients were grouped according to WC, there were significant differences only in systolic pressure, triglycerides, insulin and HOMA. Individuals with HTW had a more adverse metabolic profile than those without HTW or with only high WC. A multiple regression equation determined that body mass index, total cholesterol and diastolic blood pressure were independent predictors of insulin resistance.
Patients with HTW displayed an unfavorable cardiac risk profile.</abstract><cop>Chile</cop><pmid>20011958</pmid><doi>10.4067/S0034-98872009000900006</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Blood Pressure - physiology Body Mass Index Cardiovascular Diseases - etiology Epidemiologic Methods Female Humans Hypertriglyceridemia - blood Hypertriglyceridemia - complications Insulin Resistance - physiology Lipids - blood Male Middle Aged Risk Assessment - methods Risk Factors Waist Circumference - physiology |
title | Cardiovascular risk profile and insulin resistance according body mass index, waist circumference and hypertriglyceridemic waist in adult subjects |
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