Epidemiological, antigenic and genetic characteristics of seasonal influenza A(H1N1), A(H3N2) and B influenza viruses: Basis for the WHO recommendation on the composition of influenza vaccines for use in the 2009–2010 Northern Hemisphere season

Abstract Influenza vaccines form an important component of the global response against infections and subsequent illness caused in man by influenza viruses. Twice a year, in February and September, the World Health Organisation through its Global Influenza Surveillance Network (GISN), recommends app...

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Bibliographic Details
Published in:Vaccine 2010-02, Vol.28 (5), p.1156-1167
Main Authors: Barr, Ian G, McCauley, John, Cox, Nancy, Daniels, Rod, Engelhardt, Othmar G, Fukuda, Keiji, Grohmann, Gary, Hay, Alan, Kelso, Anne, Klimov, Alexander, Odagiri, Takato, Smith, Derek, Russell, Colin, Tashiro, Masato, Webby, Richard, Wood, John, Ye, Zhiping, Zhang, Wenqing
Format: Article
Language:English
Subjects:
Allergy and Immunology
Applied microbiology
Biological and medical sciences
Epidemiology
Fundamental and applied biological sciences. Psychology
Human
Humans
Influenza
Influenza A Virus, H1N1 Subtype - genetics
Influenza A Virus, H1N1 Subtype - immunology
Influenza A Virus, H3N2 Subtype - genetics
Influenza A Virus, H3N2 Subtype - immunology
Influenza B virus - genetics
Influenza B virus - immunology
Influenza Vaccines - genetics
Influenza Vaccines - immunology
Influenza Vaccines - therapeutic use
Influenza, Human - epidemiology
Influenza, Human - genetics
Influenza, Human - immunology
Influenza, Human - prevention & control
Microbiology
Miscellaneous
Pandemics
Seasonal
Vaccine
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Virology
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Summary:Abstract Influenza vaccines form an important component of the global response against infections and subsequent illness caused in man by influenza viruses. Twice a year, in February and September, the World Health Organisation through its Global Influenza Surveillance Network (GISN), recommends appropriate influenza viruses to be included in the seasonal influenza vaccine for the upcoming Northern and Southern Hemisphere winters. This recommendation is based on the latest data generated from many sources and the availability of viruses that are suitable for vaccine manufacture. This article gives a summary of the data and background to the recommendations for the 2009–2010 Northern Hemisphere influenza vaccine formulation.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2009.11.043