Heterotopic ossification in systemic sclerosis

Although myopathy or myositis may occur in systemic sclerosis (SSc) as well as soft tissue calcification, ossification is not a feature of the disease. Here we present an unusual case of extended calcification and, to a lesser degree, ossification of the right gluteal region, lateral thigh, and knee...

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Bibliographic Details
Published in:Scandinavian journal of rheumatology 2009, Vol.38 (4), p.317-319
Main Authors: Botzoris, V. G., Argyropoulou, M. I., Voulgari, P. V., Zikou, A. K., Drosos, A. A.
Format: Article
Language:English
Subjects:
Acetaminophen - therapeutic use
Biological and medical sciences
Colchicine - therapeutic use
Diseases of the osteoarticular system
Drug Therapy, Combination
Etidronic Acid - analogs & derivatives
Etidronic Acid - therapeutic use
Humans
Knee Joint - pathology
Male
Medical sciences
Middle Aged
Ossification, Heterotopic - complications
Ossification, Heterotopic - diagnostic imaging
Ossification, Heterotopic - drug therapy
Ossification, Heterotopic - pathology
Pain Measurement
Prognosis
Risedronate Sodium
Risk Assessment
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Scleroderma, Systemic - complications
Scleroderma, Systemic - diagnostic imaging
Scleroderma, Systemic - drug therapy
Scleroderma, Systemic - pathology
Severity of Illness Index
Thigh - pathology
Tomography, X-Ray Computed
Treatment Outcome
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Description
Summary:Although myopathy or myositis may occur in systemic sclerosis (SSc) as well as soft tissue calcification, ossification is not a feature of the disease. Here we present an unusual case of extended calcification and, to a lesser degree, ossification of the right gluteal region, lateral thigh, and knee, with associated myopathy and functional impairment. Heterotopic ossification (HO), or myositis ossificans, has not been reported so far in scleroderma patients, making this case, in our opinion, unique and interesting. However, differential diagnosis from other causes of extraskeletal ossification, such as tumours or tumour-like conditions, is required.
ISSN:0300-9742
1502-7732
DOI:10.1080/03009740902776919