Comorbidity and gender-related differences in patients hospitalized for COPD. The ECCO study

Summary Rationale Patients hospitalized for a COPD exacerbation are usually of advanced age, with functional deterioration, and suffering an increased number of associated conditions, but little is known about gender differences. Our hypothesis is that the frequency and type of comorbidities differ...

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Bibliographic Details
Published in:Respiratory medicine 2010-02, Vol.104 (2), p.253-259
Main Authors: Almagro, P, López García, F, Cabrera, FJ, Montero, L, Morchón, D, Díez, J, Soriano, JB
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Alcoholism - epidemiology
Biological and medical sciences
Cardiac failure
Cardiology. Vascular system
Cardiovascular Diseases - epidemiology
Chronic Disease
Chronic obstructive pulmonary disease, asthma
Comorbidity
COPD
Epidemiologic Methods
Female
Gender
Heart
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Hospitalization
Humans
Male
Medical sciences
Middle Aged
Pneumology
Pulmonary Disease, Chronic Obstructive - epidemiology
Pulmonary/Respiratory
Respiratory Function Tests
Spain - epidemiology
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Summary:Summary Rationale Patients hospitalized for a COPD exacerbation are usually of advanced age, with functional deterioration, and suffering an increased number of associated conditions, but little is known about gender differences. Our hypothesis is that the frequency and type of comorbidities differ in male and female COPD patients. Material and methods A cross-sectional, multicentre study of patients hospitalized for a COPD exacerbation. All of them had COPD confirmed by baseline forced spirometry with a bronchodilator test. Comorbidity information was collected using the Charlson index, and an ad hoc questionnaire that included other common conditions not included in the Charlson index. Results We studied 398 patients, 353 men (89%) and 45 women (11%), with a mean (S.D.) age of 73.7 (8.9) years and a percent predicted FEV1 of 43.2 (12.5). The mean score of the Charlson index was 2.7 (2.0), with no differences by gender; in contrast, the mean number of all comorbid conditions assessed was 3.7 (1.7) in men and 1.8 (1.8) in women ( p  
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2009.09.019