Acute bacterial meningitis in infants and children

Summary Bacterial meningitis continues to be an important cause of mortality and morbidity in neonates and children throughout the world. The introduction of the protein conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae , and Neisseria meningitidis has changed the ep...

Full description

Saved in:
Bibliographic Details
Published in:The Lancet infectious diseases 2010, Vol.10 (1), p.32-42
Main Author: Kim, Kwang Sik, Prof
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Bacteria
Bacterial diseases
Bacterial diseases of the nervous system. Bacterial myositis
Biological and medical sciences
Child
Epidemiology
Human bacterial diseases
Humans
Infant
Infants
Infectious Disease
Infectious diseases
Medical sciences
Meningitis, Bacterial - drug therapy
Meningitis, Bacterial - epidemiology
Meningitis, Bacterial - microbiology
Neonates
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c528t-2e3c2afbc6cbbb9fe3d4b81ac0ba0146fd2b28aa52143d45d9f41bff3f1d7cd13
cites cdi_FETCH-LOGICAL-c528t-2e3c2afbc6cbbb9fe3d4b81ac0ba0146fd2b28aa52143d45d9f41bff3f1d7cd13
container_end_page 42
container_issue 1
container_start_page 32
container_title The Lancet infectious diseases
container_volume 10
creator Kim, Kwang Sik, Prof
description Summary Bacterial meningitis continues to be an important cause of mortality and morbidity in neonates and children throughout the world. The introduction of the protein conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae , and Neisseria meningitidis has changed the epidemiology of bacterial meningitis. Suspected bacterial meningitis is a medical emergency and needs empirical antimicrobial treatment without delay, but recognition of pathogens with increasing resistance to antimicrobial drugs is an important factor in the selection of empirical antimicrobial regimens. At present, strategies to prevent and treat bacterial meningitis are compromised by incomplete understanding of the pathogenesis. Further research on meningitis pathogenesis is thus needed. This Review summarises information on the epidemiology, pathogenesis, new diagnostic methods, empirical antimicrobial regimens, and adjunctive treatment of acute bacterial meningitis in infants and children.
doi_str_mv 10.1016/S1473-3099(09)70306-8
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_734281187</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1473309909703068</els_id><sourcerecordid>1933226181</sourcerecordid><originalsourceid>FETCH-LOGICAL-c528t-2e3c2afbc6cbbb9fe3d4b81ac0ba0146fd2b28aa52143d45d9f41bff3f1d7cd13</originalsourceid><addsrcrecordid>eNqFkF1rFTEQhoNY7If-BGURRL1YzSTZ3eRGKaXaQqEX6nXIx0RT92Rrsiv035tz9lihN0IgIfPkzcxDyHOg74BC__4LiIG3nCr1hqq3A-W0b-UjclSvRStENzzenVfkkByXckMpDEDFE3LIKDBVq0eEnbplxsYaN2OOZmw2mGL6HudYmpjqCibNpTHJN-5HHH3G9JQcBDMWfLbfT8i3T-dfzy7aq-vPl2enV63rmJxbhtwxE6zrnbVWBeReWAnGUWsoiD54Zpk0pmMgaqnzKgiwIfAAfnAe-Al5vebe5unXgmXWm1gcjqNJOC1FD1wwCSCHSr58QN5MS061OV0n7ZkQXFWoWyGXp1IyBn2b48bkOw1Ub5XqnVK99aWp0julWtZ3L_bhi92gv3_112EFXu0BU5wZQzbJxfKPY5xK3veV-7hyWKX9jph1cRGTQx8zuln7Kf63lQ8PEtwYU6yf_sQ7LPdDgy5M0zVkm0HVLkHyP2vaptk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>201624439</pqid></control><display><type>article</type><title>Acute bacterial meningitis in infants and children</title><source>ScienceDirect Freedom Collection</source><creator>Kim, Kwang Sik, Prof</creator><creatorcontrib>Kim, Kwang Sik, Prof</creatorcontrib><description>Summary Bacterial meningitis continues to be an important cause of mortality and morbidity in neonates and children throughout the world. The introduction of the protein conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae , and Neisseria meningitidis has changed the epidemiology of bacterial meningitis. Suspected bacterial meningitis is a medical emergency and needs empirical antimicrobial treatment without delay, but recognition of pathogens with increasing resistance to antimicrobial drugs is an important factor in the selection of empirical antimicrobial regimens. At present, strategies to prevent and treat bacterial meningitis are compromised by incomplete understanding of the pathogenesis. Further research on meningitis pathogenesis is thus needed. This Review summarises information on the epidemiology, pathogenesis, new diagnostic methods, empirical antimicrobial regimens, and adjunctive treatment of acute bacterial meningitis in infants and children.</description><identifier>ISSN: 1473-3099</identifier><identifier>EISSN: 1474-4457</identifier><identifier>DOI: 10.1016/S1473-3099(09)70306-8</identifier><identifier>PMID: 20129147</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>London: Elsevier Ltd</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Bacteria ; Bacterial diseases ; Bacterial diseases of the nervous system. Bacterial myositis ; Biological and medical sciences ; Child ; Epidemiology ; Human bacterial diseases ; Humans ; Infant ; Infants ; Infectious Disease ; Infectious diseases ; Medical sciences ; Meningitis, Bacterial - drug therapy ; Meningitis, Bacterial - epidemiology ; Meningitis, Bacterial - microbiology ; Neonates</subject><ispartof>The Lancet infectious diseases, 2010, Vol.10 (1), p.32-42</ispartof><rights>Elsevier Ltd</rights><rights>2010 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>2010 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Jan 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c528t-2e3c2afbc6cbbb9fe3d4b81ac0ba0146fd2b28aa52143d45d9f41bff3f1d7cd13</citedby><cites>FETCH-LOGICAL-c528t-2e3c2afbc6cbbb9fe3d4b81ac0ba0146fd2b28aa52143d45d9f41bff3f1d7cd13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,4012,27910,27911,27912</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=22308366$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20129147$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Kwang Sik, Prof</creatorcontrib><title>Acute bacterial meningitis in infants and children</title><title>The Lancet infectious diseases</title><addtitle>Lancet Infect Dis</addtitle><description>Summary Bacterial meningitis continues to be an important cause of mortality and morbidity in neonates and children throughout the world. The introduction of the protein conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae , and Neisseria meningitidis has changed the epidemiology of bacterial meningitis. Suspected bacterial meningitis is a medical emergency and needs empirical antimicrobial treatment without delay, but recognition of pathogens with increasing resistance to antimicrobial drugs is an important factor in the selection of empirical antimicrobial regimens. At present, strategies to prevent and treat bacterial meningitis are compromised by incomplete understanding of the pathogenesis. Further research on meningitis pathogenesis is thus needed. This Review summarises information on the epidemiology, pathogenesis, new diagnostic methods, empirical antimicrobial regimens, and adjunctive treatment of acute bacterial meningitis in infants and children.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Bacteria</subject><subject>Bacterial diseases</subject><subject>Bacterial diseases of the nervous system. Bacterial myositis</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Epidemiology</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infant</subject><subject>Infants</subject><subject>Infectious Disease</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Meningitis, Bacterial - drug therapy</subject><subject>Meningitis, Bacterial - epidemiology</subject><subject>Meningitis, Bacterial - microbiology</subject><subject>Neonates</subject><issn>1473-3099</issn><issn>1474-4457</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqFkF1rFTEQhoNY7If-BGURRL1YzSTZ3eRGKaXaQqEX6nXIx0RT92Rrsiv035tz9lihN0IgIfPkzcxDyHOg74BC__4LiIG3nCr1hqq3A-W0b-UjclSvRStENzzenVfkkByXckMpDEDFE3LIKDBVq0eEnbplxsYaN2OOZmw2mGL6HudYmpjqCibNpTHJN-5HHH3G9JQcBDMWfLbfT8i3T-dfzy7aq-vPl2enV63rmJxbhtwxE6zrnbVWBeReWAnGUWsoiD54Zpk0pmMgaqnzKgiwIfAAfnAe-Al5vebe5unXgmXWm1gcjqNJOC1FD1wwCSCHSr58QN5MS061OV0n7ZkQXFWoWyGXp1IyBn2b48bkOw1Ub5XqnVK99aWp0julWtZ3L_bhi92gv3_112EFXu0BU5wZQzbJxfKPY5xK3veV-7hyWKX9jph1cRGTQx8zuln7Kf63lQ8PEtwYU6yf_sQ7LPdDgy5M0zVkm0HVLkHyP2vaptk</recordid><startdate>2010</startdate><enddate>2010</enddate><creator>Kim, Kwang Sik, Prof</creator><general>Elsevier Ltd</general><general>Lancet Publishing Group</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8C2</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>2010</creationdate><title>Acute bacterial meningitis in infants and children</title><author>Kim, Kwang Sik, Prof</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c528t-2e3c2afbc6cbbb9fe3d4b81ac0ba0146fd2b28aa52143d45d9f41bff3f1d7cd13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Bacteria</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the nervous system. Bacterial myositis</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Epidemiology</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infant</topic><topic>Infants</topic><topic>Infectious Disease</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Meningitis, Bacterial - drug therapy</topic><topic>Meningitis, Bacterial - epidemiology</topic><topic>Meningitis, Bacterial - microbiology</topic><topic>Neonates</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Kwang Sik, Prof</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Virology and AIDS Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Lancet Titles</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>The Lancet infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Kwang Sik, Prof</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acute bacterial meningitis in infants and children</atitle><jtitle>The Lancet infectious diseases</jtitle><addtitle>Lancet Infect Dis</addtitle><date>2010</date><risdate>2010</risdate><volume>10</volume><issue>1</issue><spage>32</spage><epage>42</epage><pages>32-42</pages><issn>1473-3099</issn><eissn>1474-4457</eissn><coden>LANCAO</coden><abstract>Summary Bacterial meningitis continues to be an important cause of mortality and morbidity in neonates and children throughout the world. The introduction of the protein conjugate vaccines against Haemophilus influenzae type b, Streptococcus pneumoniae , and Neisseria meningitidis has changed the epidemiology of bacterial meningitis. Suspected bacterial meningitis is a medical emergency and needs empirical antimicrobial treatment without delay, but recognition of pathogens with increasing resistance to antimicrobial drugs is an important factor in the selection of empirical antimicrobial regimens. At present, strategies to prevent and treat bacterial meningitis are compromised by incomplete understanding of the pathogenesis. Further research on meningitis pathogenesis is thus needed. This Review summarises information on the epidemiology, pathogenesis, new diagnostic methods, empirical antimicrobial regimens, and adjunctive treatment of acute bacterial meningitis in infants and children.</abstract><cop>London</cop><pub>Elsevier Ltd</pub><pmid>20129147</pmid><doi>10.1016/S1473-3099(09)70306-8</doi><tpages>11</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1473-3099
ispartof The Lancet infectious diseases, 2010, Vol.10 (1), p.32-42
issn 1473-3099
1474-4457
language eng
recordid cdi_proquest_miscellaneous_734281187
source ScienceDirect Freedom Collection
subjects Anti-Bacterial Agents - therapeutic use
Bacteria
Bacterial diseases
Bacterial diseases of the nervous system. Bacterial myositis
Biological and medical sciences
Child
Epidemiology
Human bacterial diseases
Humans
Infant
Infants
Infectious Disease
Infectious diseases
Medical sciences
Meningitis, Bacterial - drug therapy
Meningitis, Bacterial - epidemiology
Meningitis, Bacterial - microbiology
Neonates
title Acute bacterial meningitis in infants and children
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T13%3A09%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Acute%20bacterial%20meningitis%20in%20infants%20and%20children&rft.jtitle=The%20Lancet%20infectious%20diseases&rft.au=Kim,%20Kwang%20Sik,%20Prof&rft.date=2010&rft.volume=10&rft.issue=1&rft.spage=32&rft.epage=42&rft.pages=32-42&rft.issn=1473-3099&rft.eissn=1474-4457&rft.coden=LANCAO&rft_id=info:doi/10.1016/S1473-3099(09)70306-8&rft_dat=%3Cproquest_cross%3E1933226181%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c528t-2e3c2afbc6cbbb9fe3d4b81ac0ba0146fd2b28aa52143d45d9f41bff3f1d7cd13%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=201624439&rft_id=info:pmid/20129147&rfr_iscdi=true