Interrelationship between lactate and cardiac fatty acid metabolism

This overview is presented, in the main, to summarize the following aspects of lactate and cardiac fatty acid metabolism: 1. The utilization of exogenous carbohydrates and fatty acids by the heart. 2. The competition between lactate and fatty acids in cardiac energy metabolism. 3. The effect of lact...

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Published in:Molecular and cellular biochemistry 1992-10, Vol.116 (1-2), p.11-17
Main Authors: van der Vusse, G J, de Groot, M J
Format: Article
Language:English
Subjects:
Animals
Carbohydrate Metabolism
Dogs
Energy Metabolism
Fatty Acids - metabolism
Heart - diagnostic imaging
Homeostasis
Humans
Lactates - metabolism
Lactic Acid
Myocardial Ischemia - metabolism
Myocardium - metabolism
Radionuclide Imaging
Rats
Swine
Triglycerides - metabolism
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cites cdi_FETCH-LOGICAL-c282t-e1c0ad386fc661a20814cbcf14c93137edc4ff1f314cb6f1ae32b9afcda4e3383
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description This overview is presented, in the main, to summarize the following aspects of lactate and cardiac fatty acid metabolism: 1. The utilization of exogenous carbohydrates and fatty acids by the heart. 2. The competition between lactate and fatty acids in cardiac energy metabolism. 3. The effect of lactate on endogenous triacylglycerol homeostasis. 4. Lactate-induced impairment of functional recovery of the post-ischemic heart. 5. The effect of lactate on lipid metabolism in the ischemic and post-ischemic heart. 6. The consequences of hyperlactaemia for cardiac imaging.
doi_str_mv 10.1007/BF01270563
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subjects Animals
Carbohydrate Metabolism
Dogs
Energy Metabolism
Fatty Acids - metabolism
Heart - diagnostic imaging
Homeostasis
Humans
Lactates - metabolism
Lactic Acid
Myocardial Ischemia - metabolism
Myocardium - metabolism
Radionuclide Imaging
Rats
Swine
Triglycerides - metabolism
title Interrelationship between lactate and cardiac fatty acid metabolism
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