Insulin and GH secretion in adolescent girls with irregular cycles: Polycystic vs multifollicular ovaries

In the present study insulin (I) and GH secretion was studied in a group of twenty-five young adolescent girls (mean age: 15 +/- 0.23 yr) with cycle irregularity associated to clinical signs of hyperandrogenism in comparison with that observed in eleven normal matched subjects with regular menses. A...

Full description

Saved in:
Bibliographic Details
Published in:Journal of endocrinological investigation 2003-04, Vol.26 (4), p.305-311
Main Authors: VILLA, P, ROSSODIVITA, A, FULGHESU, A. M, CUCINELLI, F, BARINI, A, APA, R, BELOSI, C, LANZONE, A
Format: Article
Language:English
Subjects:
Adolescent
Area Under Curve
Biological and medical sciences
Diagnosis, Differential
Female
Female genital diseases
Glucose Tolerance Test
Growth Hormone-Releasing Hormone - physiology
Gynecology. Andrology. Obstetrics
Human Growth Hormone - blood
Humans
Hyperandrogenism - blood
Hyperinsulinism - physiopathology
Insulin - blood
Luteinizing Hormone - blood
Medical sciences
Menstrual Cycle - blood
Menstruation Disturbances - blood
Menstruation Disturbances - classification
Menstruation Disturbances - diagnostic imaging
Non tumoral diseases
Ovarian Cysts - blood
Ovarian Cysts - diagnostic imaging
Ovary - diagnostic imaging
Polycystic Ovary Syndrome - blood
Polycystic Ovary Syndrome - diagnostic imaging
Testosterone - blood
Tumors
Ultrasonography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In the present study insulin (I) and GH secretion was studied in a group of twenty-five young adolescent girls (mean age: 15 +/- 0.23 yr) with cycle irregularity associated to clinical signs of hyperandrogenism in comparison with that observed in eleven normal matched subjects with regular menses. All patients underwent basal hormone measurements and, on two consecutive days, an oral glucose tolerance test (OGTT) and a GHRH iv test. Therefore, all subjects had a transabdominal US scan for the measurement of ovarian volume and the characterization of ovarian morphology. On the basis of the US examination we found patients with polycystic ovaries (PCO-like group) and subjects with multifollicular ovaries (MFO group). PCO-like group exhibited T (p
ISSN:0391-4097
1720-8386
DOI:10.1007/BF03345177