Wegener's granulomatosis presenting with otologic and neurologic symptoms: clinical and pathological correlations

A case of Wegener's granulomatosis in a 59‐year‐old woman is reported. The disease first involved the parotid gland, the brain stem and the spinal cord, then running a rapidly progressive course as systemic pathology. Anti‐neutrophil cytoplasmic antibody (cANCA) levels raised as renal failure s...

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Bibliographic Details
Published in:Journal of oral pathology & medicine 2003-08, Vol.32 (7), p.438-440
Main Authors: Bucolo, Sebastiano, Torre, Valerio, Montemagno, Alberto, Beatrice, Fabio
Format: Article
Language:English
Subjects:
Antibodies, Antineutrophil Cytoplasmic - analysis
Biological and medical sciences
Brain Diseases - diagnosis
Brain Diseases - pathology
Cranial Nerve Diseases - diagnosis
Cranial Nerve Diseases - pathology
Dentistry
Disease Progression
Female
Granulomatosis with Polyangiitis - diagnosis
Granulomatosis with Polyangiitis - pathology
Hearing Disorders - diagnosis
Hearing Disorders - pathology
Humans
Medical sciences
Middle Aged
neurologic symptoms
Non tumoral diseases
Otitis Media - diagnosis
Otitis Media - pathology
otologic symptoms
Otorhinolaryngology. Stomatology
Parotid Diseases - diagnosis
Parotid Diseases - pathology
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Spinal Cord Diseases - diagnosis
Spinal Cord Diseases - pathology
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
Wegener's granulomatosis
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Summary:A case of Wegener's granulomatosis in a 59‐year‐old woman is reported. The disease first involved the parotid gland, the brain stem and the spinal cord, then running a rapidly progressive course as systemic pathology. Anti‐neutrophil cytoplasmic antibody (cANCA) levels raised as renal failure set in. Renal biopsy confirmed the diagnosis of Wegener's granulomatosis and an appropriate therapy was adopted.
ISSN:0904-2512
1600-0714
DOI:10.1034/j.1600-0714.2003.t01-1-00152.x