Blackgram fiber (Phaseolus mungo): Mechanism of hypoglycemic action

The effect of the administration of blackgram fiber (Phaseolus mungo) on the metabolism of carbohydrates was studied in rats fed 30% NDF (neutral detergent fiber) diet. The experimental group showed a significant increase in liver glycogen level and a significant decrease in blood glucose. Significa...

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Bibliographic Details
Published in:Plant foods for human nutrition (Dordrecht) 2003-01, Vol.58 (1), p.7-13
Main Authors: BOBY, R. G, LEELAMMA, S
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Blood Glucose - analysis
Carbohydrate Metabolism
Detergents
Dietary Fiber - administration & dosage
Dietary Fiber - metabolism
Feeding. Feeding behavior
Fundamental and applied biological sciences. Psychology
Glycemic Index
Hypoglycemic Agents - administration & dosage
Hypoglycemic Agents - metabolism
Liver - enzymology
Liver - metabolism
Liver Glycogen - analysis
Male
Phaseolus - chemistry
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Rats
Rats, Sprague-Dawley
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:The effect of the administration of blackgram fiber (Phaseolus mungo) on the metabolism of carbohydrates was studied in rats fed 30% NDF (neutral detergent fiber) diet. The experimental group showed a significant increase in liver glycogen level and a significant decrease in blood glucose. Significant increases in the activities of glycogen phosphorylase, hexokinase, fructose-1, 6-diphosphatase, glucose-6-phosphate dehydrogenase and isocitrate dehydrogenase were observed in the experimental group. The activities of phosphoglucomutase and glucose-6-phosphatase were significantly lower in rats fed the fiber diet. The study showed that blackgram fiber exhibits significant hypoglycemic action in experimental animals.
ISSN:0921-9668
1573-9104
DOI:10.1023/A:1024023909383