Delineating the sites and progression of in vivo atrophy in multiple system atrophy using fluid-registered MRI

We describe the pattern and progression of atrophy delineated using fluid registration of serial magnetic resonance imaging scans in a case of multiple system atrophy (MSA). The in vivo findings were consistent with those found at postmortem, including significant supratentorial atrophy concurrent w...

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Bibliographic Details
Published in:Movement disorders 2003-08, Vol.18 (8), p.955-958
Main Authors: Schott, Jonathan M., Simon, Jessica E., Fox, Nick C., King, Andrew P., Khan, M. Nadeem, Cipolotti, Lisa, Paviour, Dominic C., Stevens, John M., Rossor, Martin N.
Format: Article
Language:English
Subjects:
Atrophy - pathology
Biological and medical sciences
Brain - pathology
Cognition Disorders - diagnosis
Cognition Disorders - etiology
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Disease Progression
Fatal Outcome
Humans
magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Medical sciences
Middle Aged
multiple system atrophy
Multiple System Atrophy - complications
Multiple System Atrophy - pathology
Neurology
Neuropsychological Tests
supratentorial atrophy
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Summary:We describe the pattern and progression of atrophy delineated using fluid registration of serial magnetic resonance imaging scans in a case of multiple system atrophy (MSA). The in vivo findings were consistent with those found at postmortem, including significant supratentorial atrophy concurrent with an unusual degree of cognitive impairment for MSA. © 2003 Movement Disorder Society
ISSN:0885-3185
1531-8257
DOI:10.1002/mds.10468