Oral pemphigus vulgaris associated with HIV infection

Vesiculobullous disease in association with HIV infection is extremely rare. This report details the presentation and management of pemphigus vulgaris in an individual with HIV infection. The clinical characteristics and response to therapy appear not to be modified by coexistent HIV infection. Howe...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2003-08, Vol.49 (2), p.313-315
Main Authors: Hodgson, Tim A, Fidler, Sarah J, Speight, Paul M, Weber, Jonathan N, Porter, Stephen R
Format: Article
Language:English
Subjects:
Adult
Antiretroviral Therapy, Highly Active
Biological and medical sciences
Bullous diseases of the skin
Cyclosporine - therapeutic use
Dermatology
Disease Progression
HIV Infections - complications
HIV Infections - drug therapy
Human viral diseases
Humans
Immunosuppressive Agents - therapeutic use
Infectious diseases
Male
Medical sciences
Pemphigus - drug therapy
Pemphigus - etiology
Pemphigus - pathology
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:Vesiculobullous disease in association with HIV infection is extremely rare. This report details the presentation and management of pemphigus vulgaris in an individual with HIV infection. The clinical characteristics and response to therapy appear not to be modified by coexistent HIV infection. However, the management of pemphigus vulgaris relies on immunosuppressive therapy potentially resulting in HIV disease progression. Cyclosporine has in vitro antiretroviral activity and, currently, should be considered as a possible treatment for individuals with pemphigus vulgaris and HIV infection.
ISSN:0190-9622
1097-6787
DOI:10.1067/S0190-9622(03)00413-4