Seroprevalence of tetanus antibody in Turkish population and effectiveness of single-dose tetanus toxoid

The study presented here was performed to determine the rates of immunity to tetanus in a cross section of the Turkish population and to assess the impact of a single-dose tetanus toxoid in previously unvaccinated individuals. Among 18-year-old participants who received their last tetanus booster 4...

Full description

Saved in:
Bibliographic Details
Published in:European journal of clinical microbiology & infectious diseases 2003-07, Vol.22 (7), p.431-433
Main Authors: CAVUSLU, S, ONCUL, O, ALTUNAY, H, OZSOY, M. F, KOCAK, N
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antibodies, Bacterial - blood
Bacterial diseases
Bacterial diseases of the nervous system. Bacterial myositis
Biological and medical sciences
Clostridium tetani - immunology
Female
Human bacterial diseases
Humans
Immunization
Infectious diseases
Male
Medical sciences
Prospective Studies
Seroepidemiologic Studies
Tetanus
Tetanus - epidemiology
Tetanus - immunology
Tetanus - prevention & control
Tetanus Antitoxin - analysis
Tetanus Antitoxin - blood
Tetanus Toxoid
Turkey - epidemiology
Vaccines
Young adults
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The study presented here was performed to determine the rates of immunity to tetanus in a cross section of the Turkish population and to assess the impact of a single-dose tetanus toxoid in previously unvaccinated individuals. Among 18-year-old participants who received their last tetanus booster 4 years prior to the study and 22-year-old participants who received the booster 8 years previously, certain durable protective antibody (>1 IU/ml) was detected in 100%. However, only 3.3% of 20-year-old participants who did not know whether they had been vaccinated as children or young adults had a protective antibody level. After administering a single dose of tetanus vaccine to this group, the rate of protective antibody increased from 3.3% to 96.7%. For the prevention of tetanus, the optimal policy should focus on improving rates of complete primary immunization in adults and children and giving a single booster every 10 years, or at least at age 40 or 50 years.
ISSN:0934-9723
1435-4373
DOI:10.1007/s10096-003-0954-y