Laboratory Semen Assessment and Prediction of Fertility: still Utopia?

Contents Finding a laboratory test reliable enough to predict the potential fertility of a given semen sample or a given sire for artificial insemination (AI) is still considered utopian, as indicated by the modest correlations seen between results obtained in vitro and field fertility. Male fertili...

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Bibliographic Details
Published in:Reproduction in domestic animals 2003-08, Vol.38 (4), p.312-318
Main Author: Rodríguez-Martínez, H
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Female
Fertility
Flow Cytometry - standards
Fundamental and applied biological sciences. Psychology
Male
Mammalian reproduction. General aspects
Predictive Value of Tests
Pregnancy
Semen - cytology
Semen - physiology
Sperm Count
Sperm Motility
Vertebrates: reproduction
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Summary:Contents Finding a laboratory test reliable enough to predict the potential fertility of a given semen sample or a given sire for artificial insemination (AI) is still considered utopian, as indicated by the modest correlations seen between results obtained in vitro and field fertility. Male fertility is complex, and depends upon a heterogeneous population of spermatozoa interacting at various levels of the female genital tract, the vestments of the oocyte, and the oocyte itself. For this reason, laboratory assessment of semen must include the testing of most sperm attributes relevant for fertilization and embryo development, not only in individual spermatozoa but within a large sperm population as well. Strategies for the discovery of in vitro predictors of semen fertility require evaluations of low sperm doses for AI, so that differences in innate in vivo fertility can be accurately detected.
ISSN:0936-6768
1439-0531
DOI:10.1046/j.1439-0531.2003.00436.x