Electrochemical preparation of chitosan/hydroxyapatite composite coatings on titanium substrates

Composite coatings containing brushite (CaHPO4 · 2H2O) and chitosan were prepared by electrochemical deposition. The brushite/chitosan composites were converted to hydroxyapatite/chitosan composites in aqueous solutions of sodium hydroxide. The coatings ranged from ≈1 to 15% chitosan by weight. Qual...

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Bibliographic Details
Published in:Journal of biomedical materials research 2003-08, Vol.66A (2), p.411-416
Main Authors: Redepenning, Jody, Venkataraman, Guhanand, Chen, Jun, Stafford, Nathan
Format: Article
Language:English
Subjects:
Biological and medical sciences
brushite
Calcium Phosphates - chemistry
Chitin - analogs & derivatives
Chitin - chemical synthesis
Chitosan
Coated Materials, Biocompatible - chemical synthesis
composite
Durapatite - chemical synthesis
Electrochemistry
electrodeposition
Hot Temperature
hydroxyapatite
Medical sciences
Microscopy, Electron, Scanning
Microspheres
Time Factors
Titanium
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Summary:Composite coatings containing brushite (CaHPO4 · 2H2O) and chitosan were prepared by electrochemical deposition. The brushite/chitosan composites were converted to hydroxyapatite/chitosan composites in aqueous solutions of sodium hydroxide. The coatings ranged from ≈1 to 15% chitosan by weight. Qualitative assessment of the coatings showed adhesion significantly improved over that observed for electrodeposited coatings of pure HA. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res 66A: 411–416, 2003
ISSN:1549-3296
0021-9304
1552-4965
1097-4636
DOI:10.1002/jbm.a.10571